Generally, students admitted in the Life Sciences and Physical & Mathematical Sciences streams include chemistry in their first year, in addition to one or more mathematics courses. CHM151Y is the course that is strongly recommended for all students who will be following one of the six chemistry specialist programs and for those who will be including a substantial amount of chemistry in their degree (such as in the chemistry major program). Please note that first year biology and/or physics courses are additional requirements towards the six specialist programs.
The combination of CHM135H and CHM136H is recommended for students who intend to take programs in the Life or Health Sciences that do not require a large amount of chemistry. These are also the most appropriate courses for students applying for entry into professional programs.
The second-year courses introduce students to their chosen field of studies in physical, organic, inorganic, environmental, analytical and pharmaceutical chemistry.
The third-year courses offer the students a wide variety of selection to concentrate on their chosen field of specialization by enhancing their understanding of the chemistry in the classes and strengthening their practical experience in the laboratories.
The fourth-year courses cement student understanding and practical experience to prepare them for employment upon graduation, or to pursue independent work in graduate studies.
Click on the links below to view the course descriptions. The academic calendar lists the course requirements like pre-requisites, co-requisites and exclusions, and the timetable when the courses are offered.
100 Level Courses
CHM101H1-The Chemistry and Biology of Organic Molecules: Sex, Drugs and Rock and Roll - Not Currently Offered
| Title | CHM101H1 - The Chemistry and Biology of Organic Molecules: Sex, Drugs and Rock and Roll |
| Topics |
An introduction to chemistry and chemical principles for non-scientists, with a focus on the chemistry and biology of organic molecules. The myriad roles these compounds play in our lives are discussed, including their use of pheromones, medicines and weapons, and their effect on colour, taste and smell. |
|
Title |
CHM135H1 Chemistry: Physical Principles (formerly CHM139H1) |
|---|---|
|
Schedule |
3 lectures
Notes: Offered in Fall and Winter. CHM135H1 must be successfully completed before CHM136H1 can be taken (CHM136H1 is offered during the Winter and Summer sessions only). |
|
Topics |
Structure of matter, gases, liquids and solids; phase equilibria and phase diagrams; colligative properties; chemical equilibria; electrolyte solutions and electrochemistry; reaction kinetics; introduction to thermodynamics. Recommended for students in life and health science programs that involve a small amount of chemistry. |
|
Background |
Prerequisite: Chemistry SCH4U, Mathematics MHF4U + MCV4U
|
|
Lab Fee |
This course charges a lab fee.
|
|
Course Spokesperson |
Fall 2024
Winter 2025
|
|
Lecturer |
Fall 2024
Winter 2025
Summer 2025
|
|
Lab Instructor |
Fall 2024
Winter 2025
Summer 2025
|
|
Course Outline |
2023-2024
2022-2023 |
|
Title |
CHM136H1 Introductory Organic Chemistry I (formerly CHM138H1) |
|---|---|
|
Schedule |
3 lectures
Notes: Offered in Winter & Summer sessions only. Students must successfully complete CHM135H1 before they can take CHM136H1.
|
|
Topics |
CHM135H1 and CHM136H1 cannot be taken in the same session. An introduction to principles of structure and their relation to reactivity of organic molecules: molecular structure, stereochemistry, functional groups, reactions, and mechanisms. Recommended for students in life and health science programs that involve a small amount of chemistry. |
|
Background |
Prerequisite: CHM135H1 |
|
Lab Fee |
This course charges a lab fee
|
|
Course Spokesperson |
Winter 2025
Summer 2025
|
|
Lecturer |
Winter 2025
Summer 2025 |
|
Lab Instructor |
Winter 2025
Summer 2025
|
|
Course Outline |
2024-2025 2022-2023
|
|
Title |
CHM151Y Chemistry: The Molecular Science |
|---|---|
|
Schedule |
3 lectures |
|
Topics |
An introduction to the major areas of modern chemistry, including organic and biological chemistry; inorganic/materials chemistry and spectroscopy; and physical chemistry/chemical physics. The course is highly recommended for students who plan to enrol in one of the chemistry specialist programs, or who will be including a substantial amount of chemistry in their degree (such as those following a chemistry major or minor program). The combination of CHM151Y1 and CHM249H1 serves as a full year introductory course in organic chemistry with laboratory. Note: CHM151Y1 has a unique Course Community where the undergraduate experience in chemistry is greatly enhanced through a series of workshops, research seminars, tours, outreach opportunities and social activities. 90-minute biweekly Course Community meetings are held during laboratory class hours during alternate weeks to the laboratory sessions. The lab time is reserved for CHM151Y1 activities every week of each semester. |
|
Background |
Prerequisite: Chemistry SCH4U, Mathematics MHF4U + MCV4U; Physics SPH4U recommended Corequisite: (MAT135H1/ MAT136H1)/ MAT137Y1/ MAT157Y1; (PHY131H1, PHY132H1)/ (PHY151H1, PHY152H1) recommended, but may be required for further Chemistry courses Exclusion: CHM135H1, CHM136H1, CHMA10H3, CHMA11H3, CHMB41H3, CHM110H5, CHM120H5 |
|
Lab Fee |
This course charges a lab fee. |
|
Course Spokesperson |
Fall 2024
Winter 2025
|
|
Lecturer |
Fall 2024
Winter 2025
|
|
Lab Instructor |
Fall 2024
Winter 2025
|
|
Course Outline |
2024-2025: Course Outline – TBA
|
|
Title |
CHM193H1 - Chemicals in the Environment: The Good, the Bad, and the Ugly; |
|---|---|
|
Schedule |
2 Seminar |
|
Topics |
The world is made up of chemicals: some are natural and some are invented and manufactured by humans. New chemicals are often intended to make our lives safer and easier (e.g., plastics, pesticides, personal care products) but may have unanticipated consequences once they are released into the world. In this seminar course, students will discover what properties of chemicals can lead to risks for the environment and for human health. Through discussion of how chemicals in the environment are understood by scientists, and described in popular media, students will develop improved scientific literacy to better evaluate risk in their own lives. Restricted to first-year students. Not eligible for CR/NCR option. |
|
Background |
Exclusion: CHM211H1 |
|
Lecturer |
Jennifer Murphy, Em: jen.murphy@utoronto.ca |
|
Course Outline |
2023-2024 Course Outline (CHM211H1) |
|
Title |
CHM194H1 - Science and Human Values |
|---|---|
|
Schedule |
2 Seminar |
|
Topics |
There is a tension between creativity and the search for truth, which in science can be looking for patterns in nature. With examples drawn particularly from reports of scientific discoveries that have generated controversy, this seminar course will introduce the underlying principles and history of science, as well as how science and its boundaries are evolving, and how these influence human values. Restricted to first-year students. Not eligible for CR/NCR option. |
|
Background |
Recommended Preparation: Minimum level of high school science and mathematics |
|
Lecturer |
Gilbert Walker, Em: gilbert.walker@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline |
|
Title |
CHM196H1 - The Quantum World and Its Classical Limit |
|---|---|
|
Schedule |
2 Seminar |
|
Topics |
This course seeks to demystify quantum mechanics and equip students to critically analyze popular depictions of quantum phenomena. While quantum mechanics provides a reliable description of the behavior of atoms, molecules and photons, most people are uncomfortable with some of its predictions, such as "quantum entanglement" between distant particles. In this course we will delve into key aspects of quantum mechanics and its more comfortable classical limit, focusing first on its manifestations in nature and then on fundamental issues such as uncertainty, interference, entanglement, and decoherence. This course will appeal to students with enthusiasm for physics. Restricted to first-year students. Not eligible for CR/NCR option. |
|
Background |
Recommended Preparation: High school physics and mathematics |
|
Lecturer |
Paul Brumer, Em: paul.brumer@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA |
|
Title |
CHM197H1 - Environmental Chemistry in a Sustainable World |
|---|---|
|
Schedule |
2 Seminar |
|
Topics |
Rapid and widespread industrialization is changing the chemical nature of the planet. In order to have a sustainable future, we need to manage chemicals released by humankind and understand their effects on the environment and on us. Each year, this seminar course designed for non-science students will address the fundamental science behind a specific topic in this field, such as the interactions of our energy choices and the environment, changes in water and air quality, or exposure to biologically-active synthetic chemicals such as pharmaceuticals or personal care products. Emphasis is given to reading from both the popular media and scientific literature. Restricted to first-year students. Not eligible for CR/NCR option. |
|
Background |
Recommended Preparation: Grade 12 chemistry |
|
Lecturer |
Jonathan Abbatt, Em: Jonathan.abbatt@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM198H1 – Biosensor Technology and Applications for the Non-Scientist – Not Offered in 2024-2025 |
|---|---|
|
Schedule |
2 Seminar |
|
Topics |
This breadth course introduces uses of and key ideas behind biosensor technology. Sensors will be familiar to all, playing key roles in our everyday lives, for example in touch screens or in automotive technology. Biosensor devices are fabricated from an electrical transducer which is intimately connected to a biochemical probe such as an enzyme or antibody. The idea is that a detectable electrical signal can be obtained when a target molecule or ion binds to the probe. Such a device offers many applications. These range from the detection of biological markers in blood and serum to test for genetic and infectious disease, to the selective monitoring of biomolecules for public safety, or in biotechnology or other industrial processes. Restricted to first-year students. Not eligible for CR/NCR option. |
|
Background |
Recommended Preparation: Reading of book chapter on biosensor technology |
|
Course Outline |
2022-2023: Course Outline |
|
Title |
CHM199H1 - The Contet of Chemistry: Origins, Concepts, Tools, and Challenges |
|---|---|
|
Schedule |
2 Seminar |
|
Topics |
Chemistry is a practical as well as a conceptual science that serves as the basis for applications in many other fields. The ideas and methods have evolved from diverse inputs leading to widely accepted sets of standard of facts. This collective knowledge has led to progress in the quality and understanding of life at a molecular level. While the facts of chemistry are taught in established courses, the context of what we know, the limitations and challenges of what chemistry can do and how we got to this point will be the targets for discovery by students in this course. The course will operate in a seminar model, combining presentations, readings, reports and discussions of current and historical issues. Restricted to first-year students. Not eligible for CR/NCR option. |
|
Background |
Recommended Preparation: Grade 12 level chemistry |
|
Lecturer |
Ron Kluger, Em: r.kluger@utoronto.ca |
| Course Outline | 2024-2025: Course Outline – TBA 2023-2024: Course Outline
|
200 Level Courses
|
Title |
CHM209H1 Science of the Modern Kitchen |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
The properties of different food types will be discussed, as well as how they can be manipulated in the kitchen to transform taste and texture. Concepts will be considered through the lens of the scientific method, and many of the ingredients and practices of modernist cuisine will be examined. This course is intended for students with no science background. |
|
Background |
Exclusion: CHM135H1/CHM136H1/CHM138H1/CHM139H1/CHM151Y1 Recommended Preparation: SCH4U |
|
Lecturer |
|
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM210H1 Chemistry of Environmental Change |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
This course examines the fundamental chemical processes of the Earth’s natural environment, and changes induced by human activity. Topics covered are related to the atmosphere and the hydrosphere: urban air pollution, stratospheric ozone depletion, acid rain, climate change, water resources and pollution, wastewater analysis, biogeochemistry, and inorganic metals in the environment. Skills in data analysis and visualization will be developed through an introduction to the R programming language and its use in several assignments. |
|
Background |
Prerequisite: (CHM135H1/ CHM151Y1), (MAT135H1/MAT137Y1/MAT157Y1) |
|
Lecturer |
Jen Murphy, Em: jen.murphy@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA |
|
Title |
CHM217H1 Introduction to Analytical Chemistry |
|---|---|
|
Schedule |
2.5 lectures
|
|
Topics |
Introduction to the science of chemical measurement, from sampling through analysis to the interpretation of results, including how water, food products, pharmaceuticals, and dietary supplements are analysed for content, quality, and potential contaminants. Also how to interpret experimental measurements, compare results and procedures, and calibrate analytical instrumentation. Through closely integrated classes, laboratories, and tutorials, this highly practical course introduces a variety of analytical techniques including volumetric methods, potentiometry, uv/visible and infrared spectrophotometry, flame atomic absorption spectrometry, and chromatography. Additional information can be found at http://www.chem.utoronto.ca/coursenotes/CHM217/. |
|
Background |
Prerequisite: (CHM135H1, CHM136H1)/ CHM151Y1 with a minimum grade of 63%, (MAT135H1, MAT136H1)/MAT137Y1/MAT157Y1 |
|
Lab Fee |
This course charges a lab fee. |
|
Lecturer |
Rebecca Jockusch, Em: rebecca.jockusch@utoronto.ca |
|
Lab Instructor |
David Stone, Em: david.stone@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM220H1 Physical Chemistry for Life Sciences |
|---|---|
|
Schedule |
3 lectures
|
|
Topics |
Introduction to thermodynamics; kinetics; phase equilibrium, properties of mixtures, chemical equilibrium, electrochemistry; introduction to quantum mechanics and spectroscopy. This course is recommended for students in life and health science programs that involve a small amount of chemistry. |
|
Background |
Prerequisite: (CHM135H1, CHM136H1)/ CHM151Y1; (MAT135H1, MAT136H1)/ MAT137Y1/ MAT157Y1 Corequisite: Recommended co-requisite: MAT235Y1/ MAT237Y1 Exclusion: CHM222H1, CHMB20H3, JCP221H5/ CHM221H5 |
|
Course Spokesperson |
Andrew Woolley, Em: andrew.woolley@utoronto.ca |
|
Lecturer |
Andrew Woolley, Em: andrew.woolley@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline |
|
Title |
CHM222H1 Introduction to Physical Chemistry |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
Topics: introductory thermodynamics, first and second law and applications; chemical equilibrium. The course is intended for students who will be following the majority of chemistry specialist programs (Biological Chemistry specialist students are highly recommended to take CHM220H1). |
|
Background |
Prerequisite: [(CHM135H1, CHM136H1)/ CHM151Y1 with a minimum grade of 63%], (MAT135H1, MAT136H1)/ MAT137Y1/ MAT157Y1, (PHY131H1, PHY132H1)/ ( PHY151H1, PHY152H1) Corequisite: MAT235Y1/ MAT237Y1 recommended Exclusion: CHM220H1, CHMB20H3, CHM221H5, JCP221H5 |
|
Lecturer |
Jeremy Schofield, Em: jeremy.schofield@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA |
|
Title |
CHM223H1 Physical Chemistry: The Molecular Viewpoint |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
This course introduces key concepts and mathematical approaches that underly fundamental quantum mechanical models of atoms and molecules. Connections are drawn between these microscopic models and macroscopic properties of systems in physical chemistry—both how experimental observations shape the chosen structure of the models, and how these models can now successfully predict and interpret the results of experiments. |
|
Background |
Prerequisite: CHM220H1 with a minimum grade of 63%/CHM222H1 |
|
Lecturer |
Mark Wilson, Em: mark.w.b.wilson@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
PHC230H1 Pharmaceutics I (Cross-Listed Course: PHM141H1) |
|---|---|
|
Schedule |
3 lectures |
|
Topics |
This course introduces the key concepts in the design, manufacture, and use of efficacious dosage forms. The characteristics of different delivery routes are discussed. The course focuses on the role of pharmaceutics in drug development, and the role of anatomy and physiology in the conception and design of effective dosage forms. Topics covered include biopharmaceutical considerations, pharmaceutical solutions, sterilization theories and techniques, complexation and solubility enhancement, pre-formulation, colloids and dispersions, powders and micromeritics, and solid-state properties. Students will gain an appreciation of how the properties of drug components (such as pH, salt concentration, co-solvents, sterility, colloids, dispersions, powders, and solids) determine the stability, solubility, and efficacy of drug products.. |
|
Background |
Prerequisite: CHM135H1 + CHM136H1/CHM151Y1; CHM220H1/CHM222H1 Exclusion: PHM141H1 |
| Course Spokesperson |
|
|
Lecturer |
|
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline |
|
Title |
CHM236H1 Introductory Inorganic Chemistry I |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
Inorganic chemistry is the chemistry of all the periodic table elements and includes the synthesis of the largest volume chemicals on Earth, the key energy-generating reactions and catalysts needed for a green planet, and compounds exploited in modern electronic and photonic devices. This is the first part (followed by CHM237H1 and then CHM338H1) of a two-year sequence illustrating the rich variety of structures, physical properties, and reactions of compounds of the elements across and down the periodic table. It includes fundamentals of bonding, symmetry, and acid-base/ redox reactions of molecular compounds and transition metal complexes and applications of this chemistry in the world. CHM236H1 is recommended for students interested in broadly learning about chemistry across the periodic table. |
|
Background |
Prerequisite: CHM151Y1/(CHM135H1, CHM136H1) with a minimum grade of 63% Exclusion: CHM231H5, CHM238Y1, CHMB31H3 |
|
Lecturer |
Robert Morris, Em: robert.morris@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline |
|
Title |
CHM237H1 Introductory Inorganic Chemistry II |
|---|---|
|
Schedule |
2 lectures Notes: Offered in Winter session only. Students must successfully complete CHM236H1 before they can take CHM237H1. |
|
Topics |
This course is a continuation from CHM236H1 which further studies the chemistry of the elements across the periodic table. It will cover topics that include the periodic properties of the elements, the structures, bonding and properties of main group compounds and transition metal complexes, inorganic solid-state materials, and solid-state chemistry with applications in advanced technologies. A strong emphasis on developing laboratory techniques and communication skills is made through the practical component of the course. CHM236H1 is strongly recommended for students exploring experimental synthetic chemistry as part of their degree program. |
|
Background |
Prerequisite: CHM236H1 with a minimum grade of 63% Exclusion: CHM231H5, CHM238Y1, CHMB31H3 |
|
Lab Fee |
This course charges a lab fee. |
|
Lecturer |
|
|
Lab Coordinator |
|
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline |
|
Title |
CHM247H1 Introductory Organic Chemistry II |
|---|---|
|
Schedule |
3 lectures 3.5 (A) labs 1 tutorial Note: Offered in Winter and Summer sessions only |
|
Topics |
Reactions of organic compounds. Principles of mechanism, synthesis, and spectroscopy, continuing from CHM136H1. This course is recommended for students in life and health science programs that involve a small amount of chemistry. Students who will be including a substantial amount of chemistry in their degree (including those following a chemistry major program) are strongly encouraged to take CHM249H1. |
|
Background |
Prerequisite: (CHM135H1, CHM136H1)/ CHM151Y1 |
|
Lab Fee |
This course charges a lab fee. |
|
Course Spokesperson |
Winter 2025
Summer 2024
|
|
Lecturer |
Winter 2025
Summer 2025
|
|
Lab Instructor |
Winter 2025
Summer 2025
|
|
Course Outline |
2023-2024: Winter Course Outline - TBA, Summer Course Outline - TBA |
|
Title |
CHM249H1 - Organic Chemistry |
|---|---|
|
Schedule |
3 lectures |
|
Topics |
An introductory course in organic chemistry, based around the themes of structure, bonding, reaction mechanism, and synthesis. Reactions are discussed with a view to understanding mechanisms and how they are useful in the multi-step synthesis of medicinally and industrially important compounds. An introduction to the spectroscopy of organic molecules is also given, as well as a discussion of topics relating to the biological behaviour of organic molecules and medicinal chemistry. Students are also introduced to green chemistry approaches from an experimental perspective. This course continues from CHM151Y1 or CHM136H1 and is designed for students enrolled in any chemistry specialist or major program. |
|
Background |
Prerequisite: CHM151Y1/ (CHM135H1, CHM136H1) with a minimum grade of 63% |
|
Lab Fee |
This course charges a lab fee. |
|
Lecturer |
|
|
Lab Instructor |
|
|
Course Outline |
2024-2025: Course Outline - TBA |
JCC250H1 - Computing for Science - Not Currently Offered
|
Title |
JCC250H1 - Computing for Science |
|---|---|
|
Topics |
Computational skills for the modern practice of basic and applied science. Applied computer programming with an emphasis on practical examples related to the simulation of matter, drawing from scientific disciplines including chemistry, biology, materials science, and physics. Studio format with a mixture of lecture, guided programming, and open scientific problem solving. Students will be exposed to Python numerical and data analysis libraries. No prior programming experience is required. |
| Background |
Prerequisite: CHM135H1/ CHM136H1/ CHM151Y1 0.5 credit in MAT (excluding FYF courses) |
CHM295H1 - Research Experience in Chemstry - New for 2024-2025
|
Title |
CHM295H1 - Research Experience in Chemistry |
|---|---|
| Schedule | 1 lecture 4 labs
|
|
Topics |
A course-based undergraduate research experience (CURE) that will introduce students to experimental research in chemistry from a physical science perspective, involving measurement, use of scientific instruments, and data analysis. Students will collaborate in teams to acquire research skills by carrying out laboratory work on a specific project that is defined by various chemistry departmental research groups. The topics will cover a range of research areas; however the approach will include aspects of physical chemistry such as spectroscopy, thermodynamics, nanotechnology, properties of materials, and reaction kinetics. Training in the use of instruments and data acquisition and analysis will be provided. |
| Background | Prerequisite: ( CHM135H1, CHM136H1)/ CHM151Y1, ( MAT135H1, MAT136H1)/ MAT137Y1/ MAT157Y1), ( PHY131H1, PHY132H1)/ ( PHY151H1, PHY152H1) Corequisite: CHM220H1/ CHM222H1 |
| Lab Fee | This course charges a lab fee. |
| Lecturer |
Cynthia Goh, Em: cynthia.goh@utoronto.ca |
| Lab Instructor |
Cynthia Goh, Em: cynthia.goh@utoronto.ca |
| Course Outline | 2024-2025: Course Outline - TBA |
|
Title |
CHM299H1 - Research Opportunity Program |
|---|---|
|
Topics |
Credit course for supervised participation in faculty research project. Details at https://www.artsci.utoronto.ca/current/academics/research-opportunities/research-opportunities-program. Not eligible for CR/NCR option.ble for CR/NCR option. |
| Title | CHM299Y1 – Research Opportunity Program |
| Topics |
Credit course for supervised participation in faculty research project. Details at https://www.artsci.utoronto.ca/current/academics/research-opportunities/research-opportunities-program. Not eligible for CR/NCR option. |
300 Level Courses
|
Title |
PHC300H1 – Molecular Pharmacology I (Cross-Listed Course: PHM323H1) |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
Structural and mechanistic determinants of drug action at the molecular level. Topics include the physical-chemical properties of drugs per se as they relate to therapeutic intervention and the biophysical and biochemical properties of enzymes and nucleic acids that underlie and are affected by their interactions with drugs. |
|
Background |
Prerequisite: CHM135H1 + CHM136H1/CHM151Y1; CHM220H1/CHM222H1 Exclusion: PCL302H1 |
|
Lecturer |
|
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline |
|
Title |
JSC301H1 - Principles and Practices in Science Education |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
Fundamental principles and practices in education and public outreach in the sciences, mathematics, and engineering, including education research, curriculum, teaching, and assessment. Students will learn and apply effective strategies which engage and educate learners at the K-16 and public level. The course assignments include a project and/or placement experience. |
| Background | Prerequisite: At least 8.0 credits, and enrolment in a science, mathematics, or engineering program |
|
Lecturer |
|
| Course Outline | 2024-2025: Course Outline - TBA 2023-2024: Course Outline |
|
Title |
PHC301H1 – Molecular Pharmacology II (Cross Listed Course: PHM140H1) |
|---|---|
|
Schedule |
3 lectures |
|
Topics |
Structural and mechanistic determinants of drug action via macromolecules that effect cellular signalling. Neurohumoral receptors and other signalling proteins are grouped according to their structure and mechanism of action. Native properties and their modulation by drugs are discussed in the context of basic principles of molecular pharmacology.. |
|
Background |
Prerequisite: CHM135H1 + CHM136H1/CHM151Y1 CHM220H1/CHM222H1; BCH210H1 Exclusion: PCL302H1, PHM140H1 |
|
Coodinator |
Rob Bonin, Em: rob.bonin@utoronto.ca |
|
Lecturer |
|
|
Course Outline |
2024-2025: Course Outline - TBA |
|
Title |
CHM310H1 - Environmental Fate and Toxicity of Organic Contaminants |
|---|---|
|
Schedule |
2 lectures 1 tutorial |
|
Topics |
Organic chemical contaminants surround us in our everyday lives (e.g. in medications, personal care products, flame retardants, refrigerants) and because of this, they are present in the environment and in ourselves. In this course we will explore the fate of chemicals in the environment as a whole, as well as in the body, to understand how chemicals can be designed to mitigate the risks associated with their use and unintended release. Specific topics will include environmental partitioning; environmentally-relevant transformation processes; the chemistry and effects of redox-active species; and the toxicity/detoxification of electrophilic species in the body. Skills in big data analysis and environmental modeling will be developed through an introduction to the R programming language at the beginner level. |
|
Background |
Prerequisite: (CHM135H1, CHM136H1)/CHM151Y1, CHM247H1/ CHM249H1, (MAT135H1, MAT136H1)/MAT137Y1/MAT157Y1 |
|
Lecturer |
Jessica D’eon, Em: jessica.deon@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA |
|
Title |
CHM317H1 – Introduction to Instrumental Methods of Analysis |
|---|---|
|
Schedule |
2 lectures
|
|
Topics |
Scope of instrumental analytical chemistry; Fourier transform IR absorption spectroscopy; molecular luminescence; emission spectroscopy; mass spectrometry; sensors; gas and high-performance liquid chromatography; instrument design principles and applications in industry and the environment. |
|
Background |
Prerequisite: CHM217H1 with a minimum grade of 63%; (MAT135H1, MAT136H1)/MAT137Y1/MAT157Y1 |
|
Lab Fee |
This course charges a lab fee. |
|
Lecturer |
Rebecca Jockusch, Em: rebecca.jockusch@utoronto.ca
|
|
Lab Instructor |
David Stone, Em: david.stone@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
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Title |
PHC320H1 Medicinal Chemistry |
|---|---|
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Schedule |
3 lectures |
|
Topics |
This course provides interdisciplinary learning related to the chemistry of drugs and technologies of drug discovery as they are related to small molecules and biologics, their mechanisms of action, and the latest trends in the field of pharmaceuticals. Various important concepts such as structure-activity relationships, drug-like properties, computer modelling, combinatorial chemistry, small molecule drugs, biologics and related aspects in relation to new drugs will be covered. Novel concepts such as artificial intelligence in drug discovery will be introduced. After completing this course, students may practice entry-level medicinal chemistry with sound synthetic chemistry acquired from other chemistry courses, or take advanced courses in medicinal chemistry, drug discovery, and specialized courses in drug development. Students will also have a deeper understanding of drug discovery and development. |
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Background |
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Lecturer |
Lakshmi Kotra, Em: p.kotra@utoronto.ca |
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Course Outline |
2024-2025: Course Outline - TBA |
|
Title |
CHM326H1 - Introductory Quantum Mechanics and Spectroscopy |
|---|---|
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Schedule |
2 lectures 1 tutorial |
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Topics |
This course introduces the postulates of quantum mechanics to develop the fundamental framework of quantum theory. A number of exactly soluble problems are treated in detail as examples. Perturbation theory is introduced in the context of understanding many body problems. Various applications to chemical bonding and molecular spectroscopy are covered in detail. |
|
Background |
Prerequisite: CHM220H1/CHM222H1, CHM223H1), MAT235Y1/MAT237Y1 |
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Lecturer |
Al-Amin Dhirani, Em: a.dhirani@utoronto.ca |
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Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
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Title |
CHM327H1 – Experimental Physical Chemistry |
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Schedule |
1 lecture 4 labs |
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Topics |
Students are introduced to physical chemistry laboratory work in a project-based approach in which they develop, design, and implement projects that address fundamental and applied questions in physical chemistry. The course also involves class material related to working as an experimental physical chemist. |
|
Background |
Prerequisite: (CHM220H1/CHM222H1/MSE202H1, CHM223H1) with a minimum grade of 63% in each |
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Lab Fee |
This course charges a lab fee. |
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Lecturer |
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Lab Instructor |
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| Course Outline | 2024-2025: Course Outline - TBA 2023-2024: Course Outline |
|
Title |
CHM328H1 - Modern Physical Chemistry |
|---|---|
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Schedule |
2 lectures 1 tutorial |
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Topics |
This course explores the microscopic description of macroscopic phenomena in chemistry. Statistical mechanics is introduced as the bridge between the microscopic and macroscopic views, and applied to a variety of chemical problems including reaction dynamics. More advanced topics in thermodynamics are introduced and discussed as required. |
|
Background |
Prerequisite: CHM220H1/CHM222H1, CHM223H1, MAT235Y1/MAT237Y1 |
|
Lecturer |
Anatole von Lilienfeld, Em: anatole.vonlilienfeld@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline |
|
Title |
PHC330H1 Pharmaceutics II |
|---|---|
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Schedule |
3 lectures |
|
Topics |
This course provides an understanding of advanced topics in pharmaceutics. It involves a detailed examination of the material properties of pharmaceuticals and the role of cellular processes in the delivery of a drug to its site of action. Selected topics include thermodynamic characterization of drug solubility, diffusion measurement and its use in pharmaceutics, liposomal drug delivery, excipient consideration and selection for liquid dosage forms, polymeric materials in pharmaceutical applications, rheology and its applicability to liquid drug vehicles, bioequivalence determination of dermatological dosage forms, and an introduction on the impact of physiochemical properties on dermatological dosage forms. |
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Background |
Prerequisite: CHM135H1, CHM136H1/CHM151Y1; CHM220H1/CHM222H1 |
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Coordinator |
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Lecturer |
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Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline |
PHC331H1 Establishing the Bioequivalence of Pharmaceutical Products - Not offered during 2024-2025
|
Title |
PHC331H1 Establishing the Bioequivalence of Pharmaceutical Products |
|---|---|
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Schedule |
4 lectures |
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Topics |
This course will introduce the practical and regulatory design elements and consideration of human clinical trials for the purposes of demonstrating bioequivalence between drug products. The principles discussed are currently used by generic and innovator drug companies in many countries. Students will learn about the regulations, methods, techniques, pharmacokinetics, and biostatistics involved in creating bioequivalence studies. The course has a heavy mathematical emphasis, with a large component dedicated to mathematical modeling (non-compartmental and compartmental pharmacokinetic modeling, and biostatistics). Also discussed are clinical trial sample size determination, bioequivalence study design elements, clinical study protocol and final report writing, disaster recovery and outlier analysis, and design of steady-state studies. A module is also included on developing and improving interview skills. After taking this course, students will understand the steps required to set up single-dose and steady-state pilot and pivotal bioequivalence trials using parallel, crossover, and semi-replicate designs, and be well-poised for entry-level scientific positions in industry. |
|
Background |
Prerequisite: BCH210H1, CHM247H1/CHM249H1, (MAT135H1, MAT136H1)/MAT137Y1, PHC230H1, PHC330H1 |
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Course Outline |
2023-2024: Course Outline 2022-2023: Course Outline |
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Title |
CHM338H1 - Intermediate Inorganic Chemistry |
|---|---|
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Schedule |
2 lectures |
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Topics |
Further study of the structures, physical properties, and reactions of transition metals. Introductions to spectroscopy, structural analysis, reaction mechanisms, d-block organometallic compounds, applications of metal, and main group compounds in catalysis. The weekly laboratory explores advanced synthetic and spectroscopic techniques including air- and moisture-sensitive chemistry and multinuclear NMR spectroscopy, with a strong emphasis on developing scientific communication skills. |
|
Background |
Prerequisite: CHM236H1 + CHM237H1 with a minimum grade of 63% in each course. Exclusion: CHM331H5 Exclusion: CHM217H1, CHM247H1/CHM249H1 |
|
Lab Fee |
This course charges a lab fee. |
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Lecturer |
Datong Song, Em: d.song@utoronto.ca |
|
Lab Instructor |
John De Backere, Em: john.debackere@utoronto.ca
|
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
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Title |
PHC340Y1 Pharmaceutical Chemistry Laboratory |
|---|---|
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Schedule |
2 lectures |
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Topics |
This course will introduce students to theoretical and applied concepts in pharmaceutical chemistry, in research, development, and manufacturing contexts. The course is designed with lectures and laboratories covering major areas in pharmaceutical chemistry, which have been carefully scheduled together to link concepts discussed during lectures to practical hands-on activities. The course covers selected topics pertinent to drug development such as acid/base equilibria, buffer preparation, drug solubility, drug polymorphs and salt selection, pKa, and co-solvency. The course also examines characterizing properties of common liquid, semi-solid and solid drug vehicles, such as viscosity, degradation kinetics/stability, diffusivity, tonicity, particle size distribution, and powder flowability. Emphasis is placed on the process of drug manufacture. Laboratory equipment used is commonly found in formulation labs, pharmacies, pharmaceutical research laboratories, and pharmaceutical manufacturing facilities. A lecture module on ethics and academic integrity will discuss cutting-edge applications of ethics in research, and issues arising when complex scientific solutions are proposed to regulatory bodies and to the public eye. |
|
Background |
Prerequisite: CHM247H1/CHM249H1; ( CHM220H1/CHM222H1), CHM223H1; BCH210H1 |
| Coordinator | Fall
Winter
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Lecturer |
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Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline |
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Title |
CHM342H1 - Modern Organic Synthesis |
|---|---|
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Schedule |
2 lectures 1 tutorial |
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Topics |
An overview of the preparation of various classes of organic compounds. Strategies and tactics of synthetic organic chemistry using examples from natural products and pharmaceuticals. C-C bond formation, functional group reactivity, structure, stereochemistry and selectivity. |
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Background |
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Lecturer |
Robert Batey, Em: rob.batey@utoronto.ca
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Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
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Title |
CHM343H1 - Organic Synthesis Techniques |
|---|---|
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Schedule |
2 lectures |
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Topics |
This laboratory course showcases modern organic synthesis techniques and introduces chemical research principles. It provides excellent preparation for a CHM499Y1 project in organic chemistry. Associated classes teach theory and problem-solving approaches from a practical perspective and through industrial case studies. Green chemistry decision-making is a central theme of both the class and laboratory components. |
|
Background |
Prerequisite: CHM247H1/CHM249H1 with a minimum grade of 63% |
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Lab Fee |
This course charges a lab fee. |
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Lecturer |
Kylie Luska, Em: kylie.luska@utoronto.ca |
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Lab Instructor |
Andrew Dicks, Em: andrew.dicks@utoronto.ca
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|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM347H1 - Organic Chemistry of Biological Compounds |
|---|---|
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Schedule |
2 lectures 1 tutorial |
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Topics |
An organic chemical approach to the structure and reactions of major classes of biological molecules: carbohydrates, amino acids, peptides and proteins, phosphates, lipids, heterocycles, vitamins, nucleotides, and polynucleotides. This is achieved through studies of advanced stereochemistry, chemical modification, reactions, and synthesis. In addition to classes and reading from texts, there will be opportunities for independent written assignments on several of the topics. |
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Background |
Prerequisite: CHM247H1/CHM249H1 |
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Lecturer |
Jik Chin, Em: jik.chin@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM348H1 Organic Reaction Mechanisms |
|---|---|
|
Schedule |
2 lectures |
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Topics |
Principles and methods of analyzing and predicting organic chemical reactivity: advanced stereochemistry, conformational analysis, molecular orbitals, reaction kinetics, isotope effects, linear free energy relationships, orbital transformations, systematization of mechanisms. The laboratory section is used to illustrate the operation of the principles, including examples of data acquisition for mechanistic analysis and theoretical computations. Regular original reports on methods and outcomes are an important part of the laboratory. |
|
Background |
Prerequisite: CHM247H1/CHM249H1 with a minimum grade of 63% |
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Lab Fee |
This course charges a lab fee. |
|
Lecturer |
Ronald Kluger, Em: r.kluger@utoronto.ca |
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Lab Instructor |
Andrew Dicks, Em: andrew.dicks@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM355H1 - Introduction to Inorganic and Polymer Materials Chemistry (formerly CHM325H1) |
|---|---|
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Schedule |
2 lectures 1 tutorial |
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Topics |
Fashioned to illustrate how inorganic and polymer materials chemistry can be rationally used to synthesize superconductors, metals, semiconductors, ceramics, elastomers, thermoplastics, thermosets and polymer liquid crystals, with properties that can be tailored for applications in a range of advanced technologies. Coverage is fairly broad and is organized to crosscut many aspects of the field. |
|
Background |
Prerequisite: CHM220H1/CHM222H1, (CHM236H1, CHM237H1), CHM247H1/CHM249H1 |
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Course Spokesperson |
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Lecturer |
|
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Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM379H1 - Biomolecular Chemistry |
|---|---|
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Schedule |
2 lectures |
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Topics |
This course provides an opportunity to learn core techniques in biological chemistry in a small group laboratory setting. It provides excellent preparation for a CHM499Y1 project in biological chemistry or related areas. Classes will discuss the theory behind the techniques and highlight how they are used in modern biological chemistry research and practice. Note: CHM379H1 can be used as the biochemistry lab requirement for students completing double majors in chemistry and biochemistry. |
|
Background |
Prerequisite: (CHM247H1/CHM249H1 with a minimum grade of 63%), CHM347H1, BCH210H1 Exclusion: BCH370H1, CHM371H5 Recommended Preparation: CHM217H1 |
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Lab Fee |
This course charges a lab fee. |
|
Lecturer |
|
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Lab Instructor |
|
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM395Y1 - Research Project in Chemistry |
|---|---|
|
Schedule |
180 labs Note: Enrolment in this course is limited and application for admission should be made directly to the Associate Chair, Undergraduate Studies (andrew.dicks@utoronto.ca) in the preceding Summer session (for Fall/Winter projects) or Winter session (for Summer projects). |
|
Topics |
An independent research project conducted under the direction of a teaching faculty or research faculty member in the Department during March (for Summer Session projects) and during August (for Fall/Winter Session projects): the application form is available at the Department of Chemistry website. Not eligible for CR/NCR option. |
|
Background |
Prerequisite: Completion of at least 2.0 CHM credits with a minimum cGPA of 3.0 in all CHM credits. Students are required to identify a potential faculty supervisor before contacting the Associate Chair, Undergraduate Studies for enrolment permission. Written confirmation is needed from both the Associate Chair, Undergraduate Studies and the prospective supervisor. Attendance at a mandatory safety orientation training session held during the first week of May (Summer Session projects) or September (Fall/Winter Session projects). |
|
Course Spokesperson |
Andrew Dicks, Em: andrew.dicks@utoronto.ca |
| Course Outline | 2024-2025: Course Outline - TBA 2023-2024: Course Outline
|
| Title | CHM396Y0 – Research Topic Abroad |
| Topics | Course credit for research or field studies abroad under the supervision of a faculty member. Not eligible for CR/NCR option. |
| Background | Prerequisite: At least 8.5 credits and no more than 14.0 credits, including at least 1.5 credits from 200-level Chemistry courses, or permission of the instructor. Recommended Preparation: CHM299Y1 |
| Title | CHM397H0 – Research Abroad in Chemistry |
| Topics | Independent research project in Chemistry under the supervision by a faculty member in an approved partner institution. This unique opportunity to conduct a lab-based research project is open to students in any Chemistry programs. Not eligible for CR/NCR option. |
| Background | Prerequisite: Any CHM 300-level courses with lab; permission of the Department |
| Title | CHM398H0 – Research Excursions |
| Topics |
An instructor-supervised group project in an off-campus setting. Details at https://www.artsci.utoronto.ca/current/academics/research-opportunities/research-excursions-program Not eligible for CR/NCR option |
| Title | CHM398Y0 – Research Excursions |
| Topics |
An instructor-supervised group project in an off-campus setting. Details at https://www.artsci.utoronto.ca/current/academics/research-opportunities/research-excursions-program Not eligible for CR/NCR option. |
| TItle | CHM399H1/Y1 – Research Opportunity Program |
| Topics |
Credit course for supervised participation in faculty research project. Not eligible for CR/NCR option. |
400 Level Courses
|
Title |
PHC401H1 Drug Transport Across Biological Membranes (Grad Course: JFK1122H) |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
The goal of this course is to provide students with knowledge of the molecular processes involved in drug transport across biological cell membranes with emphasis on their physiological and clinical significance. This course is restricted to Pharmaceutical Chemistry Specialist program students. |
|
Background |
Prerequisite: PHC301H1, and enrolled as a Year 4 student in the Pharmaceutical Chemistry specialist program. Corequisite: PHC300H1 Exclusion: JFK1122H |
|
Lecturer |
Reina Bendayan, Em: r.bendayan@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline |
|
Title |
CHM410H1 - Analytical Environmental Chemistry (Graduate Course: CHM1410H) |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
An analytical theory, instrumental, and methodology course focused on the measurement of pollutants in soil, water, air, and biological tissues and the determination of physical/chemical properties including vapour pressure, degradation rates, partitioning. Lab experiments involve application of theory. |
|
Background |
Prerequisite: CHM217H1, CHM210H1/CHM310H1 |
|
Lab Fee |
This course charges a lab fee. |
|
Lecturer |
Jeremy Gauthier, Em: jeremy.gauthier@mail.utoronto.ca |
|
Lab Instructor |
Jessica D’eon, Em: jessica.deon@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM414H1 – Biosensors and Chemical Sensors (Graduate Course: CHM1102H) |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
The development, design, and operation of biosensors and chemical sensors, including biosensor technology, transducer theory and operation, device design and fabrication, surface modification and methods of surface analysis, flow injection analysis and chemometrics. |
|
Background |
Prerequisite: CHM217H1/CHM220H1/CHM222H1 Recommended Preparation: CHM317H1 |
|
Lecturer |
TBA
|
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM415H1 – Topics in Atmospheric Chemistry (Graduate Course: CHM1415H) |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
Building upon the introductory understanding of atmospheric chemistry provided in CHM210H1, this course develops a quantitative description of chemical processes in the atmosphere. Modern research topics in the field are discussed, such as aerosol chemistry and formation mechanisms, tropospheric organic chemistry, the chemistry of climate including cloud formation and geoengineering, biosphere-atmosphere interactions, and the chemistry of remote environments. Mathematical models of atmospheric chemistry are developed; reading is from the scientific literature; class discussion is emphasized. |
|
Background |
Prerequisite: CHM210H1 Recommended Preparation: CHM220H1/CHM222H1, (MAT135H1, MAT136H1)/ MAT137Y1/MAT157Y1 |
|
Textbook |
TBA |
|
Lecturer |
Jonathan Abbatt, Em: jonathan.abbatt@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM416H1 – Separation Science (Graduate Course: CHM1104H) |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
This course provides theoretical and practical background useful for engaging in cutting-edge chemical separations in chemistry, biology, medicine, engineering, research, and industry. The course covers general separations concepts and principles, with an emphasis on liquid chromatography and its various modes, including partition chromatography, ion chromatography, enantiomer chromatography, size exclusion chromatography, and affinity chromatography. Other topics include materials and instrumentation, gas chromatography, supercritical fluid chromatography, electrophoresis and related techniques, and a host of miscellaneous separation (e.g., TLC, FFF, CF) and extraction (e.g., LLE, SPE, SPME) modalities. Classes are supplemented with online/virtual laboratory exercises. |
|
Background |
Prerequisite: CHM317H1 |
|
Lecturer |
David Stone, Em: david.stone@utoronto.ca |
|
Course Outl |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM417H1 - Laboratory Instrumentation (Graduate Course CHM1106H1) |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
This course provides an introduction to building and using optics- and electronics-based instrumentation for laboratory research, as well as for implementing custom software control. Class topics include passive electronic components, diodes and transistors, operational amplifiers, analogue-to-digital conversion, light sources and detectors, reflectors, refractors, polarizers, diffractors, and many others. Classes are supplemented by laboratories in which students work in teams to build fluorescent detection systems for chromatography over the course of several weeks. |
|
Background |
Recommended Preparation: CHM317H1 |
|
Lab Fee |
This course charges a lab fee. |
|
Lecturer |
Aaron Wheeler, Em: aaron.wheeler@utoronto.ca |
|
Lab Instructor |
Aaron Wheeler, Em: aaron.wheeler@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
PHC420H1 – Application of Medicinal Chemistry to Pharmacology (Cross-Listed Course: PHM240H1) |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
This course shows students the links between basic science and the drugs used therapeutically to treat clinical problems. This course is restricted to Pharmaceutical Chemistry specialist program students. |
|
Background |
Prerequisite: PHC301H1, PHC320H1, and enrolled as a Year 4 student in the Pharmaceutical Chemistry specialist program. Exclusion: PHM240H1 |
|
Lecturer |
Jack Uetrecht, Em: jack.uetrecht@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline - TBA |
PHC421H1 – Biomolecular Interactions and Thermodynamics I (Graduate Course: PHM1130H) – Not Currently Offered
|
Title |
PHC421H1 – Biomolecular Interactions and Thermodynamics I (Graduate Course: PHM1130H) |
|---|---|
|
Schedule |
3 lectures |
|
Topics |
This course will consider many of the topics presented in the first half in much greater detail including a rigorous examination of the interpretation of experimental data. This course is intended for students whose research or interest is in the thermodynamics of biological molecules. This course is restricted to Pharmaceutical Chemistry specialist program students. |
|
Background |
Prerequisite: Enrolled as a Year 4 student in the Pharmaceutical Chemistry specialist program. Exclusion: PHM1130H |
|
Course Outline |
2023-2024: Course Outline |
|
Title |
CHM423H1 - Applications of Quantum Mechanics |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
Applications of time independent and time dependent perturbation theory to atomic and molecular problems, selection of topics from WKB approximation and the classical limit; the interaction of light with matter; elementary atomic scattering theory; molecular bonding. |
|
Background |
|
|
Lecturer |
Jeremy Schofield, Em: jeremy.schofield@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
CHM427H1 – Statistical Mechanics (Graduate Course: CHM1480H) |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
Ensemble theory in statistical mechanics. Applications, including imperfect gases and liquid theories. Introduction to non-equilibrium problems. |
|
Background |
Prerequisite: CHM326H1, CHM328H1 |
|
Lecturer |
Dvira Segal, Em: dvira.segal@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
|
Title |
PHC430H1 – Recent Developments in Dosage Form Design (Cross Listed Course: PHM324H1) (Graduate Course: PHM1109H) - Not Currently Offered |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
Introduction to controlled drug delivery: Mechanisms and kinetics of controlled drug release. Fundamental theories and mathematical tools for the design of modern dosage forms. Development and applications of controlled drug delivery dosage forms. This course is restricted to Pharmaceutical Chemistry specialist program students. |
|
Background |
Prerequisite: Enrolled as a Year 4 student in the Pharmaceutical Chemistry specialist program. Exclusion: PHM324H1, PHM1109H Recommended Preparation: PHC230H1, PHC330H1, PHC340Y1 |
|
Course Outline |
2023-2024: Course Outline - TBA |
|
Title |
PHC431H1 – Selected Topics in Drug Development – Not Currently Offered |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
In-depth discussion of implementation of pharmaceutical sciences in drug development strategies. Students will apply fundamental principles of pharmaceutics and drug delivery to current problems in the pharmaceutical industry. This course is restricted to Pharmaceutical Chemistry specialist program students. |
|
Background |
Prerequisite: Enrolled as a Year 4 student in the Pharmaceutical Chemistry specialist program. Exclusion: JFK1120H Recommended Preparation: PHC230H1, PHC330H1, PHC340Y1 |
|
Title |
CHM432H1 – Organometallic Chemistry and Catalysis (Graduate Course: CHM1204H) |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
Structure, bonding, and reactions of organometallic compounds, with emphasis on basic mechanisms, and industrial processes. Addition, metalation, elimination, important catalytic cycles, electrophilic, and nucleophilic reactions are considered on a mechanistic basis. Topics on modern organometallic chemistry and catalysis are covered. |
|
Background |
Prerequisite: CHM338H1 Recommended Preparation: CHM348H1
|
|
Lecturer |
Datong Song, Em: d.song@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
|
PHC432H1 – Nanomedicines in Oncology - Not Offered in 2024-2025
| Title | PHC432H1 – Nanomedicines in Oncology |
| Scheldule | TBA |
| Topics | This course covers a range of topics that pertain to the development and application of nanomedicines in oncology. Students will gain an understanding of the biological barriers to drug delivery in oncology as well as the tremendous heterogeneity in cancer and the challenge this presents for treatment. The concepts of passive and active targeting of nanomedicines will be covered with critical assessment of the enhanced permeability and retention effect. A detailed overview of the most advanced nanotechnology-platforms for drug delivery (i.e., liposomes, block copolymer micelles and polymer-drug conjugates) will be provided with additional discussion of new emerging platforms. The integration of imaging in drug development and development of theranostics and therapeutic-diagnostic pairs will also be discussed. Special emphasis on critical evaluation of scientific literature and pre-clinical/clinical studies will be made throughout the course. |
| Background | Prerequisite: PHC230H1, PHC330H1 and enrolled as a Year 4 student in the Pharmaceutical Chemistry specialist program. |
| Course Outline | 2023-2024: Course Outline |
|
Title |
PHC435H1 – Pharmaceutical Data Acquisition and Analysis |
|---|---|
|
Schedule |
4 lectures |
|
Topics |
Application and development of devices for the purpose of collecting and analyzing experimental data in pharmaceutical development and manufacture. |
|
Background |
Prerequisite: BCH210H1, CHM247H1/CHM249H1, (MAT135H1, MAT136H1)/MAT137Y1, PHC340Y1 and enrolled as a Year 4 student in the Pharmaceutical Chemistry specialist program. |
|
Lecturer |
David Dubins, Em: d.dubins@utoronto.ca |
|
Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline |
|
Title |
CHM437H1 - Bioinorganic Chemistry (Graduate Course: CHM1363H) |
|---|---|
|
Schedule |
2 lectures |
|
Topics |
This course examines the use of metals in biology. Topics include naturally occurring and medicinal ligands; transport, uptake and control of concentration of metal ions; and physical methods of characterization of metal binding sites. The roles of metal ions in nature are discussed, including as structural and signaling elements in proteins, nucleic acids and DNA-binding complexes and proteins; as Lewis-acid centres in enzymes; as carriers of electrons, atoms and groups in redox proteins and enzymes; and as sources of biominerals; as radiopharmaceuticals. |
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Background |
Prerequisite: CHM236H1 + CHM237H1 Exclusion: CHM333H5, CHMD69H3 Recommended Preparation: CHM338H1(strongly recommended), CHM347H1/ CHM379H1 |
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Lecturer |
Robert Morris, Email: robert.morris@utoronto.ca |
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Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
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Title |
CHM440H1 - The Synthesis of Modern Pharmaceutical Agents (Graduate Course: CHM1004H1) |
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Schedule |
2 lectures |
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Topics |
This course provides an overview of reactions and synthetic strategies that are being used at different stages of the drug development process. Using representative examples from the literature, we will concentrate on synthesis of complex heterocyclic compounds. |
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Background |
Prerequisite: CHM342H1 |
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Lecturer |
Andrei Yudin, Em: andrei.yudin@utoronto.ca |
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Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
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Title |
CHM441H1 - Spectroscopic Analysis in Organic Chemistry (Graduate Course: CHM1005H1) |
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Schedule |
2 lectures |
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Topics |
Structure and stereochemistry determination using modern spectroscopic techniques. Several techniques are discussed but particular emphasis is given to NMR (1H and 13C NMR) and mass spectrometry. The approach taken emphasizes applications of these spectroscopic methods to organic problems. Students are trained to run their own spectra (IR, UV, NMR, GC-MS). |
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Background |
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Lab Fee |
This course charges a lab fee. |
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Lecturer |
Kylie Luska, Em: kylie.luska@utoronto.ca Darcy Burns, Em: darcy.burns@utoronto.ca |
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Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
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Title |
CHM443H1 - Physical Organic Chemistry (Graduate Course CHM1003H1) |
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Schedule |
2 lectures |
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Topics |
Noncovalent binding forces, solutions, and molecular recognition. Electronic structure theory and computational techniques. Reaction mechanisms: experimental probes and reactive intermediates, including carbenes and radicals. Photophysics and photochemistry of organic compounds. |
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Background |
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Lecturer |
Mark Taylor, Em: marks.taylor@utoronto.ca |
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Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
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| Title | CHM447H1 – Bio-Organic Chemistry (Graduate Course: CHM1006H) |
| Schedule | 2 lectures |
| Topics | Mechanisms in biochemical systems: Examples of biological catalysis are considered in terms of chemical mechanisms and their extensions, overcoming barriers catalytic groups in active sites, stereochemical applications, energy transfer, kinetic patterns, inhibitors, drug design, cofactors, ribozymes, and proteosomes. Related current issues are noted and discussed. The format includes class material integrated with student discussions. |
| Background | Prerequisite: CHM347H1, CHM348H1 |
| Lecturer |
Jik Chin, Em: jik.chin@utoronto.ca |
| Course Outline | 2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline |
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Title |
CHM455H1 (formerly CHM434H1) – Advanced Materials Chemistry (Graduate Course: CHM1206H) |
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Schedule |
2 lectures |
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Topics |
A comprehensive investigation of synthetic methods for preparing diverse classes of inorganic materials with properties intentionally tailored for a particular use. Begins with a primer on solid-state materials and electronic band description of solids followed by a survey of archetypical solids that have had a dramatic influence on the materials world, some new developments in materials chemistry and a look at perceived future developments in materials research and technology. Strategies for synthesizing many different classes of materials with intentionally designed structures and compositions, textures and morphologies are then explored in detail emphasizing how to control the relations between structure and property of materials and ultimately function and utility. A number of contemporary issues in materials research are critically evaluated to appreciate recent highlights in the field of materials chemistry - an emerging sub-discipline of chemistry. |
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Background |
Prerequisite: CHM325H1/ CHM355H1, CHM338H1 |
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Lecturer |
Geoffrey Ozin, Em: g.ozin@utoronto.ca |
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Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
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Title |
CHM456H1 (formerly CHM446H1) – Organic Materials Chemistry (Graduate Course: CHM1304H) |
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Schedule |
2 lectures |
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Topics |
This course covers design, synthesis, characterization and application of organic materials. Emphasis is placed on classic examples of organic materials including semiconducting polymers, molecular devices, self-assembled systems, and bioconjugates, as well as recent advances from the literature. |
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Background |
Prerequisite: CHM220H1/CHM222H1, CHM247H1/CHM249H1 |
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Lecturer |
Dwight Seferos, Em: dwight.seferos@utoronto.ca |
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Course Outline |
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Title |
CHM457H1 (formerly CHM426H1) – Polymer Chemistry (Graduate Course: CHM1300H) |
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Schedule |
2 lectures |
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Topics |
Scope of polymer chemistry. Classification of polymers. Synthesis and characterization. Polymers in solution. Thermodynamics of polymer solutions and blends, Flory-Huggins theory. Polymers in the solid state. Crystalline and amorphous polymers. Glass transition and melting temperature. Mechanical properties. Polymers as advanced materials. |
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Background |
Prerequisite: CHM220H1/CHM222H1, CHM247H1/CHM249H1 |
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Lecturer |
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Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline |
CHM458H1 - Soft Materials for Life, Energy, and the Environment (Graduate Course: CHM1307HS) - Not offered during 2024-2025
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Title |
CHM458H1 - Soft Materials for Life, Energy, and the Environment (Graduate Course: CHM1307HS) |
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Schedule |
2 lectures |
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Topics |
In the framework of a dry lab, students will analyze and interpret characterization data, extending their existing knowledge of chemical fundamentals and experimental techniques to polymeric systems. Through a combination of classes, dynamic group collaborations, and self-paced assignments, students will actively engage with peers to understand course materials (including published literature), explore how polymer innovations are commercialized, and develop a toolkit for leveraging instrumentation to investigate hypotheses in research. |
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Background |
Prerequisite: CHM247H1/CHM249H1/MSE245H1, CHM220H1/CHM222H1/CHM223H1/APS110H1 |
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Course Outline |
2022-2023: Course Outline |
| Title | PHC460H1 – Fundamentals of Drug Discovery |
| Scheldule | 2 lectures |
| Topics | Lectures by scientists from academia and industry, and student seminars based on journal articles dealing with strategies for discovering new drugs for therapy and diagnosis. This course is restricted to Pharmaceutical Chemistry specialist program students. |
| Background | Prerequisite: BIO120H1, BIO130H1, PHC301H1 and enrolled as a Year 4 student in the Pharmaceutical Chemistry program |
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| Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline - TBA |
| Title | PHC462H1 – Clinical Drug Development |
| Schedule | 2 lectures |
| Topics | This course is designed to broaden student’s understanding of the development and licensing of new drugs and how scientific principles, ethics, governmental regulations and commercial considerations are coordinated for designing clinical trails. The format involves lectures, group discussion and student presentations. This course is restricted to Pharmaceutical Chemistry specialist program students. |
| Background |
Prerequisite: PHC230H1, PHC301H1, PHC340Y1 and enrolled as a Year 4 student in the Pharmaceutical Chemistry specialist program. Exclusion: JFK1120H |
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| Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline - TBA |
| Title | PHC470H1 – Global Pharmaceutical Policy (Cross-Listed Course: PHM320H1) |
| Scheldule | 2 lectures |
| Topics | This course is designed for students who are interested in the critical analysis of global health policy and the interrelationship between global and domestic policy issues. The course will introduce students generally to the basic concepts and issues in global health with a particular focus on pharmaceutical policy. We will address key issues in health and discuss core institutional and transnational actors, how governments in different jurisdictions manage public health responsibilities, the tension between economic imperatives and health objectives, global obligations, and pressure from special interest groups. More narrowly, we will analyze a breadth of complex policies questions. Examples include: the research and development global divide, policial issues influences on pharmaceutical policy, how global commitments, such as membership in the World Trade Organization, conflict with or correspond to domestic policy directions and national sovereignty. Guest speakers will lead some sessions. This course will consist of lectures, guest discussions, case studies and student-led presentations. This is restricted to students in the Pharmaceutical Chemistry specialist program. |
| Background | Prerequisite: Enrolled as a Year 4 student in the Pharmaceutical Chemistry specialist program. Exclusion: PHM320H1, PHM1124H |
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| Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline |
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Title |
CHM479H1 - Biological Chemistry (Graduate Course: CHM1008H1) |
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Topics |
An in-depth examination of biological systems at the molecular level. Several complex, multi-component molecular machines with a central role in life will be examined. For each system studied, the focus will be on understanding the chemical mechanisms that underlie the biological activities, and how these processes fit into a cellular context. |
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Background |
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Lecturer |
Mark Nitz, Em: mark.nitz@utoronto.ca |
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Course Outline |
2024-2025: Course Outline - TBA 2023-2024: Course Outline 2022-2023: Course Outline
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| Title | PHC489Y1 – Pharmaceutical Chemistry Research |
| Scheldule | 165 labs |
| Topics | This course will provide research experience under the supervision of a Departmental staff member. The goal is to deepen the student’s understanding of the scientific basis and practical techniques relevant to modern pharmaceutical development. This course is restricted to Pharmaceutical Chemistry specialist program students. Not eligible for CR/NCR option. |
| Background | Prerequisite: Permission from the Course Coordinator and enrolled as a Year 4 student in the Pharmaceutical Chemistry specialist program. |
| Course Spokesperson |
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| Course Outline | 2024-2025: Course Outline – TBA 2023-2024: Course Outline
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Title |
CHM499Y1 - Introduction to Chemistry Research |
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Schedule |
240 labs Notes: Enrolment in this course is limited and application for admission should be made to the Department in the preceding Winter session. |
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Topics |
An experimental or theoretical research problem under the supervision of a teaching faculty or research faculty member in the Department of Chemistry. Five mandatory 90-minute professional development workshops cover aspects of academic writing, poster presentations, reading scientific literature, and job applications/interviews. Each student is required to attend a total of six one-hour research colloquia during the Fall and Winter Sessions. Applications for enrolment should be made to the Department in the preceding Winter Session: the application form is available on the Department of Chemistry website. Only students being admitted are required to contact chemistry faculty to discuss available research projects. Projects are in the areas of environmental, analytical, physical, inorganic, materials, polymer, organic and biological chemistry. Not eligible for CR/NCR option. |
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Background |
Prerequisite:Permission of the department. Minimum cGPA of 3.0 in CHM program courses. Research positions are limited. Students with strong background on courses in the sub-discipline of research interest will be given preference. Attendance at a mandatory safety orientation training session held during the first week of September. Exclusion: CHM489Y5, CHMD90Y3, MSE498Y1, PHC489Y1 |
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Course Spokesperson |
Fall 2024
Winter 2025
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| Course Outline | 2023-2024: Course Outline |