Undergraduate Courses

Generally, students admitted in the Life Sciences and Physical & Mathematical Sciences streams include chemistry in their first year, in addition to physics, math and biology courses. CHM151Y is the course that is strongly recommended for all students who will be following one of the chemistry specialist programs and who will be including a substantial amount of chemistry in their degree such as those in chemistry major program. The combination of CHM135H and CHM136H is recommended for students who intend to take programs in the Life or Health Sciences that do not require a large amount of chemistry. It is also the most appropriate course for students applying for entry into professional programs.

The second-year courses introduce the students to their chosen field of studies in biological, physical, organic, inorganic materials and analytical chemistry.

The third-year courses offer the students a wide variety of selection to concentrate on their chosen field of specialization by enhancing their understanding of the chemistry in the lectures and strengthening their practical experience in the labs.

The fourth-year courses cement the student understanding and practical experience to prepare them for employment upon graduation or pursue independent work in graduate studies.

Click on the links below to view the course descriptions. The academic calendar lists the course requirements like pre-requisites, co-requisites and exclusions, and the timetable when the courses are offered.

 


100 Level Courses


Title

CHM135H1 Chemistry: Physical Principles (formerly CHM139H)

Schedule

 

3 lectures
3 (A) labs
1 tutorials

 

Notes: Offered in Fall and Winter (remedial). CHM135H1 must be successfully completed before CHM136H1 can be taken.

 

Topics

This course is recommended for students in the life and health science programs. The course opens with the properties of light and electronic structure, a review of bonding, intermolecular forces, states of matter and solutions.  Kinetics and the principles of equilibrium, including acid and base equilibrium are discussed. The course concludes thermodynamics and electrochemistry.

Background

 

Exclusions: CHM139H, CHM151Y, CHMA11H3, CHM110H5, CHM140Y5
Pre-requisites: Chemistry SCH4U; Mathematics MHF4U + MCV4U
Co-requisites: MAT(135H, 136H)/135Y/137Y/157Y recommended, but may be required pre-requisite in 2nd year Chemistry courses; PHY(131H, 132H)/(151H, 152H) recommended

 

Textbook

Required:

 

  • Chemistry: The Molecular Nature of Matter and Change – 9th Edition by Martin Silberberg and Patricia Amateis

 

Lab Fee

 

This course charges a lab fee.

 

Course Spokesperson

 

Fall 2022

 

Winter 2023

 

Lecturer

 

Fall 2022

 

Winter 2023

Lab Instructor

 

Fall 2022

  • TBA

 

Winter 2022

 

Course Outline

 

2022-2023: Fall Course Outline - TBA, Winter Course Outline - TBA

2021-2022: Fall Course OutlineWinter Course Outline

2020-2021: Course Outline

 

 

Title 

CHM136H1 Introductory Organic Chemistry I (formerly CHM138H) 

Schedule 

 

3 lectures 
3 (A) labs 
1 tutorials 

 

Notes: Offered in Winter & Summer sessions.  Students must successfully complete CHM135H1 before they can take CHM136H1. 

 

Topics 

 

This course is recommended for students in the life and health science programs. The course commences with a review of fundamental principles in covalent bonding to understand the structure and shape of organic molecules; the concepts of molecular conformation as well as the "handedness" of shape are introduced. The relationship between the structure of organic molecules and their reactivity is then presented. This relationship will be illustrated by examining the mechanisms by which the organic chemistry of alkenes, alkyl halides and alcohols takes place. The role of acid/base chemistry in these reactions is presented throughout. 

 

Background 

 

Exclusions: CHM151Y, CHM242H5, CHMB41H3 
Pre-requisites: Chemistry SCH4U; Mathematics MHF4U + MCV4U, CHM135H1/139H1 
Co-requisites: MAT135H/135Y/137Y/157Y recommended but may be required pre-requisite in 2nd year Chemistry courses; PHY(131H, 132H)/(151H, 152H) recommended. 

 

Textbook

 

TBA

 

Lab Fee 

 

This course charges a lab fee 

 

Course Spokesperson 

 

Winter 2023 

 

Summer 2023 

  • TBA 

 

Lecturer 

 

Winter 2023

 

 

Summer 2023 

  • TBA 
     

Lab Instructor 

 

Winter 2023

  • TBA 

 

Summer 2023

  • TBA 

 

Course Outline 

 

2022-2023: Winter Course Outline - TBA, Summer Course Outline - TBA
2021-2022: Winter Course Outline, Summer Course Outline
2020-2021: Course Outline

 

Title 

CHM151Y Chemistry: The Molecular Science 

Schedule 

3 lectures 
3.5 labs 
1 tutorials 

Topics 

 

The first section of the course is an intensive study of the principles of structure and reactions of organic compounds, as well as an introduction to the importance of organic molecules in biological processes. The middle section introduces methods of structure determination, and the properties and uses of inorganic compounds including novel materials and catalysts. Finally, the last section covers important physical chemistry principles that underlie molecular structure, reactivity and energy. 

 

The laboratory introduces important chemical techniques as well as practical illustrations of class material. It consists of several experiments over the year and provides experience in physical chemistry, as well as organic and inorganic chemical reactions. 

 

An added distinguishing feature of CHM151Y is that we assume a knowledge of introductory organic chemistry as outlined in the Ontario Grade 12 curriculum.  More specifically, this includes the first three chapters of "Organic Chemistry" by J. McMurry, the required organic chemistry text for the course. 

 

Background 

 

Exclusions: CHM135H, CHM136H, CHMA10H3, CHMA11H3, CHMB41H3, CHM110H5, CHM120H5 
Pre-requisites: Chemistry SCH4U, Mathematics MHF4U + MCV4U; Physics SPH4U recommended 
Co-requisites: (MAT135H1 + MAT136H1)/137Y1/157Y1. (PHY131H1 + PHY132H1) or (PHY151H1 + PHY152H1) recommended but may be required for further Chemistry courses.

 

 

Textbook

 

Required: 

  • J. McMurry, “Organic Chemistry", 9th Edition. The accompanying study guide and solutions manual is optional.
  • M. S. Silberberg and P. Amateis, "Chemistry: The Molecular Nature of Matter and Change", 9th Edition. The accompanying solutions manual is optional. 

 

 

Lab Fee 

This course charges a lab fee. 

Course Spokesperson 

 

Fall 2022

 

Winter 2023

 

Lecturer 

 

Fall 2022 

 

Winter 2023

Lab Instructor 

 

Fall 2022

 

Winter 2023 

  • TBA 

 

Course Outline 

 

2022-2023: Course Outline – TBA
2021-2022: Course Outline
2020-2021: Course Outline

 

Title 

CHM194H1 - Science and Human Values 

Schedule 

2 Seminar 

Topics 

There is a tension between creativity and the search for truth, which in science can be looking for patterns in nature. With examples drawn particularly from reports of scientific discoveries that have generated controversy, this seminar course will introduce the underlying principles and history of science, as well as how science and its boundaries are evolving, and how these influence human values. Restricted to first-year students. Not available for CR/NCR option. 

Background 

Minimum level of high school science and mathematics 

Lecturer 

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

 

Title 

CHM195H1 – Innovative Teaching Methods in Chemistry (not currently offered)

Schedule 

2 Seminar 

Topics 

Good teaching is effective communication that engages the audience. In this breadth course, we'll explore innovative teaching in science, through an examination of the nature of science, how scientific knowledge is built, and what makes certain concepts in science problematic to the learner. Students will read and discuss relevant articles in newsmagazines, popular science sources, and educational literature. They will design and deliver mini-lessons to communicate specified scientific concepts. As a major course project, students will develop a communication tool that integrates pedagogical know-how with leading-edge chemical discoveries to produce a teaching unit for use by Ontario teachers. Restricted to first-year students. Not available for CR/NCR option.

Background 

Minimum level of high school science and mathematics 

Lecturer 

N/A

Course Outline 

N/A

Title 

CHM196H1 - The Quantum World and Its Classical Limit 

Schedule 

2 Seminar 

Topics 

This course seeks to demystify quantum mechanics and equip students to critically analyze popular depictions of quantum phenomena. While quantum mechanics provides a reliable description of the behavior of atoms, molecules and photons, most people are uncomfortable with some of its predictions, such as "quantum entanglement" between distant particles. In this course we will delve into key aspects of quantum mechanics and its more comfortable classical limit, focusing first on its manifestations in nature and then on fundamental issues such as uncertainty, interference, entanglement, and decoherence. This course will appeal to students with enthusiasm for physics. Restricted to first-year students. Not eligible for CR/NCR option.

Background 

Minimum level of high school science and mathematics 

Lecturer 

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM197H1 - Environmental Chemistry in a Sustainable World

Schedule 

2 Seminar 

Topics 

Rapid and widespread industrialization is changing the chemical nature of the planet. In order to have a sustainable future, we need to manage chemicals released by humankind, and to understand their effects on the environment and on us. Each year, this seminar course will address the fundamental science behind a specific topic in this field, such as the interactions of our energy choices and the environment, changes in water and air quality, or exposure to biologically-active synthetic chemicals such as pharmaceuticals or personal care products. Restricted to first-year students. Not eligible for CR/NCR option.

Background 

Minimum level of high school science and mathematics 

Lecturer 

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM198H1 - Biosensor Technology and Applications for the Non-Scientist 

Schedule 

2 Seminar 

Topics 

This breadth course introduces uses of and key ideas behind biosensor technology. Sensors will be familiar to all, playing key roles in our everyday lives, for example in touch screens or in automotive technology. Biosensor devices are fabricated from an electrical transducer which is intimately connected to a biochemical probe such as an enzyme or antibody. The idea is that a detectable electrical signal can be obtained when a target molecule or ion binds to the probe. Such a device offers many applications. These range from the detection of biological markers in blood and serum to test for genetic and infectious disease, to the selective monitoring of biomolecules for public safety, or in biotechnology or other industrial processes. Restricted to first-year students. Not eligible for CR/NCR option.

Background 

Reading of book chapter on biosensor technology

Lecturer 

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM199H1 - The Contet of Chemistry: Origins, Concepts, Tools, and Challenges 

Schedule 

2 Seminar 

Topics 

Rapid and widespread industrialization is changing the chemical nature of the planet. In order to have a sustainable future, we need to manage chemicals released by humankind, and to understand their effects on the environment and on us. Each year, this seminar course will address the fundamental science behind a specific topic in this field, such as the interactions of our energy choices and the environment, changes in water and air quality, or exposure to biologically-active synthetic chemicals such as pharmaceuticals or personal care products. Restricted to first-year students. Not eligible for CR/NCR option.

Background 

Minimum level of high school science and mathematics 

Lecturer

 


200 Level Courses


Title 

CHM209H1 Science of the Modern Kitchen 

Schedule 

1 lecture

Topics 

Examines the fundamental chemical and physical processes that occur during the manipulation of edible molecules, and the resulting molecular transformations that produce different tastes and textures. Concepts will be considered through the lens of the modern practices of molecular gastronomy. This course is designed for students in humanities or social science programs. 

Background 

Exclusions: CHM135H1/CHM136H1/CHM151Y1 

Textbook

  • TBA 

Lecturer 

  • TBA 

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM210H1 Chemistry of Environmental Change 

Schedule 

2 lectures 
1 tutorials 

Topics 

This course will examine the fundamental chemical processes of the Earth's natural environment, and changes induced by human activity. Topics relate to the atmosphere: urban air pollution, stratospheric ozone depletion, acid rain; the hydrosphere: water resources and pollution, wastewater analysis; biogeochemistry and inorganic metals in the environment. 

Background 

Pre-requisites: CHM135H1/CHM151Y1, MAT135H1/MAT137Y1/MAT157Y1 
Exclusions: ENV235Y1 

Textbook

  • Colin Baird and Michael Cann, Environmental Chemistry, 5th edition ISBN: 9781429277044 

Digital copy available for purchase of rent 

Lecturer 

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline

Title 

CHM217H1 Introduction to Analytical Chemistry 

Schedule 

 

2.5 lectures 
4 labs 
1(A) tutorials 

 

Topics 

 

The process of chemical measurement from sampling through analysis to the interpretation of results. Students will learn about the use of standards, methods of calibration, the statistical treatment of results, the significance of numerical values, choosing an appropriate method of analysis, and basic principles of good laboratory practice. Experiments will be drawn from important areas such as water quality, pharmaceuticals, and food & drink. A variety of techniques will be introduced, including volumetric analysis, potentiometry, UV-visible and FTIR spectrophotometry, flame atomic absorption spectrometry, and various forms of chromatography. Please see the course web site for more details.

 

https://sites.chem.utoronto.ca/chemistry/coursenotes/CHM217/

 

Background 

 
Pre-requisites: (CHM135H1 + CHM136H1)/CHM151Y1 with a minimum grade of 63%; (MAT135H, MAT136H)/MAT137Y/MAT157Y. 

Exclusions: CHM211H5, CHMB16H3 

 

 

Textbook

 

Either of:

  • Skoog, West, Holler, and Crouch, “Fundamentals of Analytical Chemistry”, 9th ed., Brooks/Cole Publishing. (print or eBook available)
  • Harvey, "Analytical Chemistry 2.1" LibreTexts™ open educational resource on-line open access textbook. (A print version of this text is also available for purchase)

Lab Fee 

 

This course charges a lab fee. 

 

Lecturer 

 

Lab Instructor 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline 

Title 

CHM211H1 Chemicals in the Environment: The Good, the Bad, and the Ugly  ***NEW for 2022-2023*** 

Schedule 

2 lectures 
1 tutorials 

Topics 

  • TBA

Background 

Exclusions: CHM135H1/CHM136H1/CHM151Y1

Textbook

  • TBA

Lecturer 

Course Outline 

2022-2023: Course Outline - TBA

Title 

CHM220H1 Physical Chemistry for Life Sciences 

Schedule 

 

3 lectures 
1 tutorials 

 

Topics 

 

Introduction to thermodynamics; kinetics; phase equilibrium, properties of mixtures, chemical equilibrium, electrochemistry; introduction to quantum mechanics and spectroscopy. This course is recommended for students in life and health science programs that involve a small amount of chemistry. Students enrolled in any chemistry specialist program (including Biological Chemistry and Environmental Chemistry) or who will be including a substantial amount of chemistry in their degree (such as those following a chemistry major program), are strongly encouraged to take CHM222H1 and CHM223H1. 

 

Background 

 
Pre-requisites: (CHM135H1/139H1 + CHM136H1/138H1)/CHM151Y1; (MAT135H + MAT136H)/MAT137Y/MAT157Y 
Co-requisites: MAT235Y/MAT237Y (Recommended) 
Exclusion: CHM225Y1/CHM222H1, CHMB20H3, JCP221H5/CHM221H5 

 

Textbook

 

  

 ISBN-10: 0815341881 

 ISBN-13: 978-0815341888 

Course Spokesperson 

Lecturer 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline

Title 

CHM222H1 Introduction to Physical Chemistry 

Schedule 

 

2 lectures 
1 tutorials 

 

Topics 

 

This course will present a systematic approach to the topic of Thermodynamics and introduce Quantum Mechanics. Lectures will be designed to teach the mathematics used in the course.

 

Background 

 

Prerequisite: (CHM135H1 + CHM136H1/CHM151Y1 with a minimum grade of 63%; (MAT135H1 + MAT136H1)/MAT137Y1/MAT157Y1, (PHY131H1 + PHY132H1)/(PHY151H1 + PHY152H1) 
Corequisite: MAT235Y1/MAT237Y1 (recommended) 

Exclusion: CHM220H1/CHM225Y1, CHMB20H3, CHM221H1, JCP221H5 

Textbook

Recommended:

 

  • Physical Chemistry: Thermodynamics, Statistical Thermodynamics, and Kinetics; 4th edition by Thomas Engel and Philip Reid

 

Lecturer 

 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline

Title 

CHM223H1 Physical Chemistry: The Molecular Viewpoint 

Schedule 

 

2 lectures 
1 tutorials 

 

Topics 

 

This course is intended as a continuation of CHM222H for students wishing to take some additional material in Physical Chemistry. The course covers topics in quantum mechanics and molecular spectroscopy. 

  

Background 

 

Prerequisite: CHM220H1 with a minimum grade of B, or CHM222H1 
Corequisite: MAT235Y1/MAT237Y1 is recommended but may be a required prerequisite in 3rd year Chemistry courses. 

Exclusion: CHM225Y1/CHM221H1, CHMB21H3 

 

Textbook

 

 

  • Alternate (Optional):  Ira N. Levine, Physical Chemistry (6th Ed.), Chapters 17‒20

            Atkins’ Physical Chemistry (11th Ed.) Foci 7‒9, 11  

Lecturer 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline 

Title 

PHC230H1 Pharmaceutics I (Cross Listed Course: PHM141H1) 

Schedule 

3 lectures 
1 tutorials 

Topics 

Achieving effective treatment of a disease while minimizing adverse effects of a drug requires rational selection, formulation and administration of an appropriate dosage form. This course teaches the scientific background and technical aspects important in dosage form design and their therapeutic applications.  This course will focus on the biopharmaceutical considerations and physiochemical foundation of various dosage forms.  Discussion will include preformulation factors (melting point, solubility, viscosity, dissolution, particle and solid state properties), rheology, pharmaceutical solutions, pharmaceutical powders, colloids and dispersions, complexation chelation, and protein binding.

Background 

Prerequisites: (CHM135H1, CHM136H1)/CHM151Y1; CHM220H1/CHM222H1
Exclusions: PHM141H1

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM236H1 Introductory Inorganic Chemistry I  ***NEW for 2022-2023*** 

Schedule 

2 lectures 
1 tutorials 

Notes: Offered in Fall session only.  CHM236H1 must be successfully completed before CHM237H1 can be taken.

Topics 

Inorganic chemistry is the chemistry of all of the elements of the periodic table and includes the synthesis of the largest volume chemicals on the earth, coordination geometries found in enzymes and oxygen carriers, the key energy-generating and pollution scrubbing reactions and catalysts needed for a green planet, and compounds with the magnetic and electronic properties that are exploited in modern electronic and photonic devices. This is the first part (followed by CHM237H and then CHM338H) of a two-year sequence in Inorganic Chemistry, designed to illustrate and systematize the rich variety of structures, physical properties, and reactions of compounds of the elements across and down the Periodic Table. It describes the origins of elements and isotopes, the structure of the multielectron atom, the periodic trends of element structure and properties, theories of bonding, acid-base and redox reactions of molecular compounds and transition metal complexes and applications of this chemistry in the world, ionic, metallic, semiconducting, and molecular solids, inorganic solid-state materials, and solid-state chemistry with applications in advanced technologies. This course is recommended for students interested in learning more broadly about the chemistry across the periodic table.

Background 

Exclusions: CHM231H5, CHMB31H3, CHM238Y1
Prerequisites: (CHM135H1+ CHM136H1)/CHM151Y1 with a minimum final grade of 63%

Textbook

  • Inorganic Chemistry, 5th Edition, C. Housecroft, Pearson, New York (2018).  Also available an eBook at vitalsource.com for example.

Lecturer 

Robert Morris, Em: robert.morris@utoronto.ca

Course Outline 

2022-2023: Course Outline - TBA

Title 

CHM237H1 Introductory Inorganic Chemistry II  ***NEW for 2022-2023*** 

Schedule 

2 lectures 
1 lab
1 tutorial 

Notes: Offered in Winter session only.  Students must successfully complete CHM236H1 before they can take CHM237H1. 

Topics 

This course is a continuation from CHM236H1 and further studies the chemistry of the elements across the periodic table. It will cover topics that include molecular symmetry, the bonding, structures, and properties of main group compounds and transition metal complexes. A strong emphasis on developing laboratory techniques and communication skills is made through the practical component of the course. CHM237H1 is strongly recommended for students exploring experimental synthetic chemistry as part of their degree program.

Background 

Exclusions: CHM231H5, CHMB31H3, CHM238Y1
Prerequisites: CHM236H1 with a minimum grade of at least 63%

Lab Fee

This course charges a lab fee.

Textbook

  • Inorganic Chemistry, by Catherine E. Housecroft and Alan G. Sharpe, 5th ed.

Lecturer 

Lab Coordinator

Course Outline 

2022-2023: Course Outline - TBA

Title 

CHM247H1 Introductory Organic Chemistry II 

Schedule 

 

3 lectures 
3.5 labs 
Note: Offered in Winter and Summer terms 

Topics 

 

This course builds significantly on content covered in CHM 136H and CHM 151Y and covers central concepts of organic reaction mechanisms, synthesis, and structure elucidation via spectroscopic methodologies. The laboratory reinforces fundamental organic chemistry techniques as well as showcasing practical illustrations of class material. Note: students taking any Chemistry specialist program (including Biological Chemistry) or who will be including a substantial amount of chemistry in their degree (such as those following a Chemistry major program) are either required to or strongly encouraged to take CHM 249H instead.

Background 

 

Exclusions: CHM249H1, CHM243H5, CHMB42H3 
Prerequisite: (CHM135H1 + CHM136H1)/CHM151Y1 

Textbook

 

Required: 

  • J. McMurry, “Organic Chemistry", 9th Edition. The accompanying study guide and solutions manual is optional.

Lab Fee 

 

This course charges a lab fee. 

Course Spokesperson 

 

Lecturer 

 

Lab Instructor 

 

  • TBA 

Course Outline 

 

2022-2023: TBA
2021-2022: Course Outline

Title 

CHM249H1 - Organic Chemistry 

Schedule 

 

3 lectures 
4 labs 

Topics 

 

This course provides a basic knowledge of the concepts of organic chemistry with an emphasis on the reactivity patterns of various functional groups, the mechanism of chemical reactions and the application of chemical reactions to the synthesis of useful products. The material is directed toward students whose main interest is in chemistry or a chemically related science. Problems will be assigned but not graded. All material presented during lectures could appear on tests or the final exam which will cover the entire course. 

Background 

 

Exclusions: CHM247H1, CHM243H5, CHMB42H3 
Pre-requisites: CHM151Y/(CHM135H +  CHM136H with a minimum grade of 63%. 

 

Textbook

 

  • TBA

Lab Fee 

 

This course charges a lab fee. 

Course Spokesperson 

Lecturer 

 

Lab Instructor 

 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

JCC250H1 - Computing for Science (not currently offered)

Schedule

3 lectures
3 tutorials

Topics 

Computational skills for the modern practice of basic and applied science. Applied computer programming with an emphasis on practical examples related to the simulation of matter, drawing from scientific disciplines including chemistry, biology, materials science, and physics. Studio format with a mixture of lecture, guided programming, and open scientific problem solving. Students will be exposed to Python numerical and data analysis libraries. No prior programming experience is required. 

Background Pre-requisites: CHM135H1/CHM136H1/CHM151Y1, 0.50 credit in MAT (excluding FYF courses)
Exclusion: Any CSC course except CSC104H1, CSC196H1, CSC197H1
Text

Required

  • TBA
Lecturer TBA

Course Weblink 

TBA

Title 

CHM299Y - Research Opportunity Program 

Topics 

The Research Opportunity Program (ROP) provides an opportunity for students in their second year (i.e., after completing at least four but not more than nine courses) to earn one 299Y course credit by participating in a faculty member's research project. 

Students wishing to apply for places in the ROP should submit ROP Application Forms to the ROP Office by mid March at the latest. Students will be informed in early May whether or not they have been accepted. Successful applicants will be registered in their 299Y course by the Program Office. The 299Y courses begin in September. 

Students will be expected to keep a journal recording meetings, progress, and what was learned about the project in particular and the nature of research in general. 

For more information about this research opportunity, please go to Research Opportunity Program, or contact the ROP Office at SS2133 Sidney Smith Hall, 416-978-0359. 

Course Weblink 

Course Info 

 


300 Level Courses


Title 

PHC300H1 Molecular Pharmacology I (Cross Listed Course: PHM323H1) 

Schedule 

2 lectures 
1 tutorial

Topics 

The proteins and nucleic acids that are the targets of most prescribed drugs can be classified according to their structure and mechanism of action at the molecular level.  In this course, basic concepts of enzyme action such as the mechanisms of enzyme catalysis, the Michaelis-Menten and pre-equilibrium equations, steady-state approximations, allostery and cooperativity will first be covered.  Major classes of therapeutic targets will then be discussed with an emphasis on their normal biochemical roles that are exploited for therapeutic intervention.  The mechanisms of action of drugs acting on enzymes (antiviral and antimicrobial agents) on nucleic acids and on the cytoskeleton (anti-cancer agents) will be of special interest.  The concept of rational cancer therapy will also be covered with examples of drugs targeting growth factors signalling pathways that are dysregulated in cancers.

Background 

 

Prerequisite: (CHM135H1 + CHM136H1)/CHM151Y; CHM220H1/CHM222H1
Exclusions: PCL302H1

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

JSC301H1 - Principles and Practices in Science Education 

Schedule 

 

2 lectures 

Topics 

 

Fundamental principles and practices in education and public outreach in the sciences, mathematics, and engineering, including education research, curriculum, teaching, and assessment. Students will learn and apply effective strategies which engage and educate learners at the K-16 and public level. The course assignments include a project and/or placement experience. 

 

Textbook

 

  • There is no formal textbook for this course.  Readings from relevant literature will be provided throughout the course.

Lecturer 

 

 

Title 

PHC301H1 Molecular Pharmacology II (Cross Listed Course: PHM140H1) 

Schedule 

3 lectures 
1 tutorials 

Topics 

This course is designed to provide pharmacy students with the pathobiology, pharmacology, pharmacotherapy and clinical pharmacokinetics required to be a practitioner in oncology, hematology and immunology therapeutics.  The course will be taught using a variety of techniques including on-line lectures, case-based learning and small interactive group learning.

Background 

Prerequisite: (CHM135H1 + CHM136H1)/CHM151Y; CHM220H1/CHM222H1; BCH210H1
Exclusions: PCL302H1, PHM140H1

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM310H1 Environmental Fate and Toxicity of Organic Contaminants 

Schedule 

 

2 lectures 

Topics 

 

Organic chemical contaminants surround us in our everyday lives (medications, personal care products, flame retardants, refrigerants…) and because of this they are present in the environment and in ourselves.  In this class we will explore the fate of chemicals in the environment as a whole, as well as in the body, to understand how chemicals can be designed to limit the risks associated with their use and unintended release.  Specific topics will include: environmental partitioning; environmentally-relevant transformation processes; the chemistry and effects of redox active species; the toxicity and detoxification of electrophilic species in the body. 

Background 

 

Prerequisite: (CHM135H1 +CHM136H1)/CHM151Y1, (MAT135H1 + MAT136H1)/MAT137Y/MAT157Y. 

Textbook

 

  • No textbook required.

 

Lecturer 

 

Course Outline 

 

2022-2023: Course Outline – TBA
2021-2022: Course Outline
2020-2021: Course Outline

Title 

CHM317H1 Introduction to Instrumental Methods of Analysis 

Schedule 

 

2 lectures 
4 labs

 

Topics 

 

CHM317S continues to cover the principles of instrumental analytical chemistry, first introduced with respect to absorption spectroscopy in CHM217F. The course will begin by reviewing the scope of use of instruments in chemical analysis and the theory and applications of ultraviolet/visible, infrared and atomic absorption spectroscopy. 
Further techniques to be discussed will be Fourier transform infrared spectroscopy; Raman spectroscopy; spectrofluorimetry; X-ray fluorescence; mass spectrometry and ion sources for mass spectrometry; the gas chromatography - mass spectroscopy interface; principles of surface characterization, vacuum ultraviolet and X-ray photoelectron spectroscopy; Auger electron emission spectroscopy, secondary ion mass spectrometry; separation techniques including gas chromatography and high performance liquid chromatography. In all these topics selected applications will be outlined in addition to the basic theory and instrumentation. 

 

Background 

 

Exclusions: CHM391H5, CHMC11H3, CHMC16H3 
Pre-requisites: CHM217H with a minimum grade of 63%; MAT(135H, 136H)/MAT137Y/MAT157Y 
Recommended preparation: (CHM220H/222H,CHM221H/223H)/CHM225Y

 

Textbook

 

  • TBA 

Lab Fee 

 

This course charges a lab fee. 

Lecturer 

 

 

Lab Instructor 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline 

Title 

PHC320H1 Medicinal Chemistry  

Schedule 

3 lectures 

Topics 

Modern discovery and synthesis of antibiotics, antineoplastics, antiviral and other therapeutic agents.

Background 

Prerequisite: BCH210H1, CHM247H1/CHM249H1
 

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM326H1 - Introductory Quantum Mechanics and Spectroscopy 

Schedule 

 

2 lectures 

Topics 

 

This course introduces the postulates of quantum mechanics to develop the fundamental framework of quantum theory. A number of exactly soluble problems are treated in detail as examples. Perturbation theory is introduced in the context of understanding many body problems. Various applications to molecular spectroscopy and dynamics are covered in detail. 

Background 

 

Exclusions: JCP321H5 
Pre-requisites: CHM225Y/(CHM220H/222H, 221H/223H), MAT235Y/237Y 

Textbook

 

Required 

 

  • Levine, QUANTUM CHEMISTRY, 7th edition.  Prentice Hall, 2009 (including Solution Manual, ISBN – 0132090856; or
  • McQuarrie’s Quantum Chemistry (Rev. 2nd edition, 2007), ISBN - 971891389504

 

Lecturer 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline

 

Title 

CHM328H1 - Modern Physical Chemistry 

Schedule 

 

2 lectures 

Topics 

 

In this continuation of CHM222H, more advanced topics in thermodynamics such as non-ideal effects are discussed. Statistical mechanics and its application to chemical problems are introduced. Reaction dynamics are analyzed from a fundamental perspective. 

Background 

 

Exclusions: JCP322H5, CHMC20H3 
Pre-requisites: CHM225Y/CHM(220H/222H, 221H/223H), MAT235Y/237Y

 

Textbook

 

  • TBA

 

Lecturer 

  • TBA

  

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline 

Title 

PHC330H1 Pharmaceutics II 

Schedule 

4 lectures 
0 tutorials 

Topics 

This course presents a detailed examination of the material properties of pharmaceuticals and the role of cellular processes in delivery of a drug to its site of action.

Background 

 

Prerequisite: (CHM135H1, CHM136H1)/CHM151Y; CHM220H1/CHM222H1

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

PHC331H1 Establishing the Bioequivalence of Pharmaceutical Products 

Schedule 

4 lectures 
 

Topics 

 

This course introduces regulatory, clinical, statistical and logistical considerations in assessing the relative bioavailabilities of formulations.  A heavy emphasis is placed on clinical trial design, and biostatistics involved in second entry drug applications to regulatory bodies.  Students will learn about the methods, regulations, techniques, pharmacokinetics, and biostatistics involved in creating bioequivalence studies, at an introductory level.  The course has a heavy mathematical bias with a component dedicated to mathematical modeling and basic programming in R-project, an open-source statistical package.  After taking this course, students will understand the steps required to set up single-dose or steady-state pilot and pivotal bioequivalence trials using parallel, crossover and replicate designs.  Students will be able to take a data set of plasma concentrations and be able to process and interpret the results of the trial.  Students will gain a deeper understanding and context of the regulatory differences involved in generic drug testing between Canada, the United States and Europe.

Background 

 

Prerequisite: BCH210H1, CHM247H1/CHM249H1, (MAT135H1, MAT136H1)/MAT137Y1, PHC230H1, PHC330H1

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM338H1 - Intermediate Inorganic Chemistry 

Course Notes 

 

CHM338H Course Notes 

Schedule 

 

2 lectures 
4 labs 

Topics 

 

Main group chemistry, spectroscopy of metal complexes, reaction mechanisms of d-block complexes, d block organometallic complexes, catalysis, introduction to bioinorganic chemistry. 

It is imperative that each student complete on-line enrolment for his/her laboratory section during the registration period (see weblink below). Laboratory class lists will be posted on the first day of classes. Students are responsible for checking these lists and reporting errors or omissions to the lab instructor. 

 

Background 

 

Exclusions: CHM331H5 
Pre-requisites: CHM236H1 + CHM237H1/CHM238Y1 with a minimum grade of 63% in each course. 
Recommended Preparation: CHM217H, CHM247H/CHM249H 

 

Textbook 

 

  • TBA 

 

Lab Fee 

 

This course charges a lab fee. 

Lecturer 

 

 

Lab Instructor 

 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline 

Title 

PHC340Y1 Pharmaceutical Chemistry Laboratory 

Schedule 

2 lectures 
4 labs 

Topics 

The scientific basis and practical techniques relevant to modern pharmaceutical development. This course is restricted to Pharmaceutical Chemistry Specialist program students.

Background 

Prerequisite: BCH210H1; CHM247H1/CHM249H1; CHM220H1/CHM222H1

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM342H1 - Modern Organic Synthesis 

Schedule 

 

2 lectures 

Topics 

 

This course provides an overview of the key reaction classes as they relate to reactivity, selectivity and utility in the synthesis of organic molecules. We will begin by reviewing key concepts from early courses in organic chemistry, move on to discuss different types of selectivity, retrosynthesis and devote most of our time to learning new reactions that will be used to make increasingly complex natural products and bioactive compounds with medicinally interesting properties. 

 

Background 

 

Exclusions: CHM345H5 
Pre-requisites: CHM247H/249H 

 

Textbook

 

  • TBA 

 

Lecturer 

 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline

Title 

CHM343H1 - Organic Synthesis Techniques 

Schedule 

 

2 lectures 
4 labs 

Topics 

 

This laboratory course showcases modern organic synthesis techniques and introduces chemical research principles. It provides excellent preparation for a CHM499Y project in organic chemistry. Associated lectures tech theory and problem-solving approaches from a practical perspective. 

Background 

 

Pre-requisites: CHM247H/CHM249H with minimum grade of 63%. 

Textbook

 

  • No textbook required.

 

Lab Fee 

 

This course charges a lab fee. 

Course Spokesperson 

 

 

Lecturer 

 

Lab Instructor 

 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM347H1 - Organic Chemistry of Biological Compounds 

Schedule 

 

3 lectures 

Topics 

 

Structure, reactions, analysis, and chemical synthesis of important biomolecules based on modern concepts of organic chemistry. Advanced stereochemistry, carbohydrates, amino acids, peptides, proteins, phosphate esters, nucleotides and nucleic acids, co-enzymes and vitamins. 

Background 

 

Prerequisite: CHM247H1/CHM249H1

Exclusion: CHM347H5, CHMC47H3

Recommended Preparation: CHM217H1

 

Textbook

 

Required:

  • Organic Chemistry by John McMurry, 8th or 9th edition

 

Lecturer 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline 

 

Title 

CHM348H1 Organic Reaction Mechanisms 

Schedule 

2 classes 
4.5 labs

Topics 

 

This course provides a foundation for understanding structure and reactivity of molecules through physical principles. You will learn widely accepted approaches and how to apply them to understanding and predicting diverse reaction patterns. The approach introduces new concepts while utilizing knowledge from prior organic chemistry courses.  Classes will address (a) principles of structure and structural dynamics (b) key concepts of molecular orbital theory that apply to structure and reactivity (c) how changes in free energy are measured to discover details of reaction mechanisms. The nature of reactive intermediates will be an ongoing conceptual focus. The laboratory component is coordinated with the classes and provides in-depth insights into key topics. As a result, students will receive a thorough preparation for advanced studies involving structure and reactivity in organic chemistry and other areas. 

Background 

 

Prerequisite:  CHM247H1/CHM249H1 with a minimum grade of 63%

Exclusion: CHM341H5, CHMC41H3

 

Textbook

Required: 

 

  • Francis A. Carey, Richard J. Sundberg, ADVANCED ORGANIC CHEMISTRY: PART A: STRUCTURE AND MECHANISMS, 5th ed. Springer, 2007 (paperback). A complete on-line edition will be available from the publisher the through the University of Toronto site license. The link will be available through the course syllabus on the Quercus site.
  • Organic Chemistry (McMurry, used in CHM 247H/CHM 249H (8th or 9th edition).

 

Lab Fee 

 

This course charges a lab fee. 

Lecturer 

 

 

Lab Instructor 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline

 

Title 

CHM355H1 - Introduction to Inorganic and Polymer Materials Chemistry (formerly CHM325H1)

Schedule 

 

2 lectures 

Topics 

 

Materials chemistry involves the study of the synthesis, properties, and applications of solid state and polymeric materials and represents a rapidly growing field. This introductory course is fashioned to illustrate how inorganic and organic polymer and solid state chemistry can be rationally used to synthesize superconductors, metals, semiconductors, ceramics, elastomers, thermo-plastics, thermosets, and polymer liquid crystals, with properties that can be tailored for applications in a range of advanced technologies. Coverage will be fairly broad and is organized to crosscut many aspects of the field. 

 

Background 

 

Pre-requisites: CHM220H/CHM222H/CHM225Y, (CHM236H1 + CHM237H1)/CHM238Y, CHM247H/CHM249H 

Exclusions: CHM325H1, CHM426H1

 

Textbook

 

  • TBA 

 

Course Spokesperson 

  • TBA

Lecturer 

  • TBA

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM379H1 - Biomolecular Chemistry 

Schedule 

2 lectures 
4 labs 

Topics 

 

This course provides an opportunity to learn core biological chemistry techniques in a laboratory setting. The progression of the lab material will model a research investigation into the structure/function relationship of an enzyme. Students will work in small teams and have an opportunity to use state-of-the art equipment. Each team will prepare and characterize a different mutant of the same enzyme. At the end of the course, the data from all the mutants will be analyzed and the correlation between the chemical structure and mechanism of action of the enzyme will be discussed. Techniques that will be used include PCR mutagenesis, recombinant protein expression, column chromatography, absorption and fluorescence spectroscopies, mass spectrometry, and computer modeling. The lecture material will provide the theory behind the laboratory experiments, and place the techniques within the context of modern biological chemistry applications. 

 

Background 

 

Prerequisite: CHM247H1/CHM249H1 with a minimum grade of 63%, CHM347H1, BCH210H1

Exclusion: BCH370H1, CHM371H5

Recommended Preparation: CHM217H1

 

Textbook

 

Recommended 

 

  • TBA

 

Lab Fee 

 

This course charges a lab fee. 

Lecturer 

 

 

Lab Instructor 

  • Hassai Cui, Em:

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM395Y1 - Research Project in Chemistry 

Schedule 

180 labs 
Notes: Enrolment in this course is limited and application for admission should be made directly to the Associate Chair, Undergraduate Studies in the preceding Summer Session. 

Topics 

An independent research project conducted under the direction of a teaching faculty or research faculty member in the Department of Chemistry. Students are expected to spend approximately 180 hours during the academic year on their research problem. 

Background 

Completion of at least 2.0 FCEs of CHM courses with a minimum cGPA of 3.0 in all CHM courses. Students are required to identify a potential faculty supervisor before contacting the Associate Chair, Undergraduate Studies for enrolment permission. Written confirmation is needed from both the Associate Chair, Undergraduate Studies and the prospective supervisor. Attendance at a mandatory safety orientation training session held during the first week of September. 

Lab Fee 

None 

Course Spokesperson 

 


400 Level Courses


Title 

PHC401H1 Drug Transport Across Biological Membranes (Grad Course: JFK1122H) 

Schedule 

2 lectures  

Topics 

The goal of this course is to provide students with knowledge of the molecular processes involved in drug transport across biological cell membranes with emphasis on their physiological and clinical significance. This course is restricted to Pharmaceutical Chemistry Specialist program students.

Background 

Prerequisite: PHC301H1 and enrolled as a Year 4 student in the Pharmaceutical Chemistry Specialist program.
Corequisite: PHC300H1
Exclusions: JFK1122H

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM410H1 - Analytical Environmental Chemistry 

Schedule 

 

2 lectures 
3.5 labs 

Topics 

 

CHM410H is an analytical theory, instrumental, and methodology course focused on the measurement of trace concentrations of pollutants in soil, water, air, and biological tissues. The course includes of overview of sample collection and preparation (extraction, clean-up, concentration, derivatization) which will be followed by a discussion of the theory and application of current use analytical techniques, including gas and liquid chromatography, mass spectrometry, and nuclear magnetic resonance spectrometry, to characterize the fate and disposition of organic contaminants in the environment. Lab sessions will allow students to apply lecture material in hands-on experimentation using modern analytical instrumentation. Students will be involved in field measurements as part of the laboratory exercise. 

 

Background 

 

Pre-requisites: CHM217H1, CHM210H/CHM310H1 
Recommended: CHM317H1 

 

Text

 

  • No Textbook Required

 

Lab Fee 

 

This course charges a lab fee. 

Course Spokesperson 

Lecturer 

Lab Instructor 

Jessica D’eon, Em: jessica.deon@utoronto.ca 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline

Title 

CHM414H1 - Biosensors and Chemical Sensors (Graduate Course: CHM 1102F) 

Schedule 

 

2 lectures 

Topics 

 

This course concerns current research and advances in analytical chemistry. There will be a strong emphasis on the principles of chemical and biological sensor technology, including different transduction mechanisms, device architectures and the necessary theoretical background material. Specific devices include electrochemical, optical (fiber-optic and surface plasmon resonance) and acoustic wave sensors. The use of molecular recognition and the chemical modification of transducer interfaces to achieve chemical selectivity (including biological, biomimetic, polymeric, self-assembled monolayer and synthetic host-guest systems) will be discussed, together with appropriate methods for surface characterization and analysis. Other topics will include flow injection and microfluidics technologies, chemometric techniques, and the so-called "electronic nose". 

Background 

 

Prerequisite: CHM217H1/CHM220H1/CHM222H1/CHM225Y1

Recommended Preparation: CHM317H1

Textbook

 

Required: 

There is no specific text for this course. Instead, students will be provided with references to relevant articles and reviews in the primary scientific literature as well as additional material provided during the course. Students having the CHM317H course text are recommended to retain it for background reading. The course includes a tutorial workshop on literature searching and electronic journal databases. 

 

Lecturer 

 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline

Title 

CHM415H1 - Topics in Atmospheric Chemistry (Graduate course: CHM 1415H1) 

Schedule 

 

2 lectures 

Topics 

 

This course builds upon the introductory understanding of atmospheric chemistry provided in CHM210H. In particular, modern research topics in the field are discussed, such as aerosol chemistry and formation mechanisms, tropospheric halogen chemistry, the chemistry of climate including cloud formation and geoengineering, biosphere-atmosphere interactions, the chemistry of remote environments, air pollution health effects. Reading is from the scientific literature; class discussion and presentations are emphasized. 

 

Background 

 

Pre-requisites: CHM210H1 
Recommended Preparation: CHM220H1/CHM222H1/CHM225Y1

 

Textbook

 

Required: 

  • Introduction to Atmospheric Chemistry by D.J. Jacob

 

Lecturer 

 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM416H1 - Separation Science (Graduate course: CHM1104H1) 

Schedule 

 

2 lectures 

Topics 

 

This course provides theoretical and practical background useful for engaging in cutting-edge chemical separations in chemistry, biology, medicine, engineering, research, and industry. The course covers general separations concepts and principles, with an emphasis on liquid chromatography and its various modes, including partition chromatography, ion chromatography, enantiomer chromatography, size exclusion chromatography, and affinity chromatography. Other topics include gas chromatography, supercritical fluid chromatography, electrophoresis and related techniques, a host of miscellaneous separation (e.g., TLC, FFF, CF) and extraction (e.g., dialysis and filtration, LLE, SPE) modalities, and materials and instrumentation for each of these techniques.

 

Background 

 

Prerequisite: CHM317H1 

 

Textbook

 

Required: 

 

  • Principles of Instrumental Analysis, Skoog, Holler and Crouch, 6th edition (Thomson & Brooks/Cole) or 7th Edition (CENGAGE Learning)
  • Introduction to Modern Liquid Chromatography, Snyder, Kirkland, Dolan, 3rd Edition (Wiley) – available electronically at the library

 

Lecturer 

 

Aaron Wheeler, Em: aaron.wheeler@utoronto.ca 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM417H1 - Laboratory Instrumentation (Graduate Course CHM1106H1) 

Schedule 

 

2 lectures 
Notes: 10 hours of lab; schedule TBD 

 

Topics 

 

This course is unique in the Chemistry canon in that it provides practical background useful for understanding, repairing, and building simple (and not-so-simple) instrumentation that is ubiquitous in the modern analytical laboratory. On the subject of electronics, the course covers voltage and current, resistors, capacitors, inductors, diodes, transistors, op-amps, digital electronics, and microprocessors. On the subject of computer programming, the course covers an introduction to programming, flowcharts, algorithms, C++ syntax, variables, functions, serial communication, and data processing. Finally, on the subject of optics, the course covers light sources, wavelength selectors, detectors, lenses, mirrors, prisms, polarizing optics, microscopy, and non-linear optics. The course includes a series of unique laboratory exercises to give you an opportunity to gain experience with the concepts and subjects discussed in the classes.

 

Background 

 

Recommended Preparation:  CHM317H1

Textbook

  • No textbook required

 

Lab Fee 

 

This course charges a lab fee. 

 

Lecturer 

 

 

Lab Instructor 

 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline 

Title 

PHC420H1 Application of Medicinal Chemistry to Pharmacology (Cross Listed Course: PHM240H1) 

Schedule 

1 lectures 

Topics 

This course will build upon basic pharmacology and medicinal chemistry to make links between the basic sciences and demonstrate how basic principles can be used to improve clinical therapy.  It will also include critical evaluation of evidence for specific mechanisms and therapies.  This course is restricted to Pharmaceutical Chemistry specialist program students.

Background 

Prerequisite: PHC301H1, PHC320H1 and enrolled as a Year 4 student in the Pharmaceutical Chemistry Specialist program.
Exclusions: PHM240H1

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

PHC421H1 Biomolecular Interactions and Thermodynamics I (Grad Course: PHM1130H) 

Schedule 

3 lectures 

Topics 

This course will consider many of the topics presented in the first half in much greater detail including a rigorous examination of the interpretation of experimental data. This course is intended for students whose research or interest is in the thermodynamics of biological molecules. This course is restricted to Pharmaceutical Chemistry specialist program students.

Background 

Prerequisite: Enrolled as a Year 4 student in the Pharmaceutical Chemistry Specialist program.
Exclusions: PHM1130H

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM423H1 - Applications of Quantum Mechanics 

Schedule 

 

2 lectures 

 

Topics 

 

The topics that will be discussed in this course include stationary and time-dependent perturbation theory, WKB approximation and the classical limit, pulsed laser spectroscopies. 

 

Background 

 

Pre-requisites: CHM326H 
Recommended: MAT223H 

 

Textbook

 

Required: 

  • Introduction to Quantum Mechanics: A Time Dependent Perspective, by David Tannor, University Science Books
  • Quantum Theory, by David Bohm, Dover Publications

 

Lecturer 

 

Paul Brumer, Em: paul.brumer@utoronto.ca 
 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

 

Title 

CHM427H1 - Statistical Mechanics (Graduate Course: CHM1480H1) 

Schedule  

 

2 lectures  

Topics  

 

The course will examine and develop the formalism of statistical mechanics with a view to describing the thermodynamics and structure of gases and liquids. The course will begin with an elementary treatment of the way in which equilibrium is approached in macroscopic systems. After a review of ensemble theory and fluctuations, these ideas will be applied to the structure of liquids (through distribution function theory) and to phase transitions.  The course will conclude with nonequilibrium thermodynamics covering Langevin dynamics and master equations. Molecular simulation methods will be introduced throughout, including molecular dynamics and Monte Carlo methods. 

Background  

 

Prerequisite: CHM326H1, CHM328H1 

Textbook

 

Recommended  

  • Mark Tuckerman, Statistical Mechanics: Theory and Molecular Simulation, Oxford Graduate Texts 

Lecturer  

 

 

Course Outline  

 

2022-2023: Course Outline - TBA 
2021-2022: Course Outline 
2020-2021: Course Outline 

Title 

PHC430H1 Recent Developments in Dosage Form Design (Cross Listed Course: PHM324H1) (Graduate Course: PHM1109H) 

Schedule 

2 lectures 

Topics 

This course introduces students to fundamental principles and mathematical tools for the design of modern dosage forms as well as new advances in the field of controlled release drug delivery.  Topics to be covered include introduction to controlled drug delivery, mechanisms and kinetics of drug release and their dependence on design parameters, biopharmaceutical aspects of controlled drug delivery, in vitro and in vivo correlations, computer-aided design of controlled release dosage forms, polymers and hydrogels for drug delivery, colloidal drug delivery systems, and measurements of drug release profiles.  This course is co-taught to graduate students, senior Pharmaceutical Chemistry students and PharmD students.

Background 

Prerequisite: Enrolled as a Year 4 student in the Pharmaceutical Chemistry Specialist program.
Exclusions: PHM324H1, PHM1109H
Recommended Preparation: PHC230H1, PHC330H1, PHC340Y1

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM432H1 - Organometallic Chemistry and Catalysis (Graduate Course: CHM1204H1) 

Schedule 

 

2 lectures 

Topics 

 

Structure, bonding, and reactions of organometallic compounds, with emphasis on basic mechanisms, and industrial processes. Addition, metalation, substitution, elimination, industrially important catalytic cycles, and electrophilic reactions are considered on a mechanistic basis. Although this course is concerned primarily with transition metal organometallic chemistry, the properties of s and p block organometallics may be considered. 

Background 

 

Prerequisite: CHM338H1
Recommended: CHM348H1

 

Textbook  

Required 

 

  • R. Crabtree, THE ORGANOMETALLIC CHEMISTRY OF THE TRANSITION METALS 6th ed, Wiley Interscience  

 

 

Lecturer 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline 

Title 

PHC435H1 Pharmaceutical Data Acquisition and Analysis  

Schedule 

4 lectures 
2 tutorials (optional)

Topics 

The goal of this course is to introduce students to theoretical and applied concepts in electronic circuitry, for the purpose of collecting and analyzing experimental data in pharmaceutics and other contexts. The course is designed as approximately half small-group didactic teaching, and half laboratory exercises to experiment with and illustrate concepts. The course discusses introductory circuit design, with an emphasis on how common components work (e.g. resistors, capacitors, diodes, transistors, operational amplifiers, and a variety of sensors) in scientific and pharmaceutical manufacturing instrumentation.

Practical and mathematical aspects of circuit design are discussed (e.g. Ohm’s Law, voltage dividers, analog vs. digital signals). There is a heavy emphasis on programming in C++, taught from an introductory level, which will complement learning activities.

Background 

Prerequisite: (BHC210H1, CHM247H1/CHM249H1, (MAT135H1, MAT136H1)/MAT137Y1, PHC340Y1 and enrolled as a Year 4 student in the Pharmaceutical Chemistry Specialist program.

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM437H1 - Bioinorganic Chemistry (Graduate Course: CHM1363H1) 

Schedule 

2 lectures 

Topics 

 

Essential elements, harmful elements, naturally occurring ligands, chelating ligands, ligands used in chelate therapy, functions of metals, principles of bioinorganic coordination chemistry, template effect, spontaneous self-assembly, properties of biological molecules, transport of metal ions, control and utilization of metal-ion concentrations, DNA binding, enzymes exploiting acid catalysis, NMR studies, developing artificial hydrolytic metalloenzymes, zinc fingers, electron transfer and energy sources for life, iron-sulfur proteins, Mossbauer spectroscopy, hydrogenases, nitrogenase, atom and group transfer chemistry, redox enzymes, biomineralization, radiopharmaceuticals. 

 

Background 

 

Prerequisite: CHM236H1 + CHM237H1 (or CHM238Y)

Exclusion: CHM333H5, CHMD69H3

Recommended Preparation: CHM338H1 (strongly recommended), CHM347H1/CHM379H1

 

Text 

 

  • Bioinorganic Chemistry by Dieter Rehder
  • Oxford University Press, 2014
  • ISBN: 9780199655199

 

 

Lecturer 

 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM440H1 - The Synthesis of Modern Pharmaceutical Agents (Graduate Course: CHM1004H1) 

Schedule 

2 lectures 

Topics 

 

Development of a modern drug is a complicated process that demands improved methods for selective transformations of organic molecules. Typically, medicinal chemistry efforts during the discovery stage focus on generating valuable structure/activity relationships for the compounds that are being screened for activity. At this stage, the main synthetic challenges pertain to the selective transformations of available building blocks into diversely functionalized derivatives. At the next stage, process chemists take over the project and face completely different issues that relate to finding the shortest and most efficient route to the candidate identified during the medicinal chemistry part of the campaign. The present course provides an overview of reactions that are being used at various stages of the drug development process. Using representative examples from the literature, we will concentrate on synthesis of complex heterocyclic compounds. 

 

Background 

Pre-requisites: CHM342H1

 

Textbook

Recommended 

  

  • TBA

 

Lecturer 

 

  • TBA

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM441H1 - Spectroscopic Analysis in Organic Chemistry (Graduate Course: CHM1005H1) 

Schedule 

 

2 lectures 
Notes: 20 lab hours (Sept-Nov) 

 

Topics 

 

The application of spectroscopic methods available to graduate students and researchers (IR, 1H NMR, 13C NMR , MS, UV) will be discussed. Practical aspects of each method will be emphasized. Students will learn how to operate IR, UV, NMR and MS instruments and will be required to run spectra for assigned organic molecules. 

 

Background 

 

Pre-requisites: CHM249H1, CHM343H1 

 

Textbook

 

  • TBA

 

Lab Fee 

 

This course charges a lab fee. 

Lecturer 

 

 

Lab Coordinator 

 

  • TBA 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline

Title 

CHM443H1 - Physical Organic Chemistry (Graduate Course CHM1003H1) 

Schedule 

2 lectures 

Topics 

 

Modern physical organic chemistry. Noncovalent binding forces, solutions, and molecular recognition. Electronic structure theory and computational techniques. Reaction mechanisms: experimental probes and reactive intermediates, including carbenes and radicals. Photophysics and photochemistry of organic compounds 

 

Background 

 

Pre-requisites: CHM220H1/CHM222H1/CHM225Y1, CHM348H1 

 

Textbook

 

  • TBA

 

Lecturer 

 

  • TBA

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM455H1 - Advanced Materials Chemistry (Graduate Course: CHM1206H) (formerly CHM434H1)

Schedule 

 

2 lectures 

 

Topics 

 

This course is designed as a natural follow-up to Materials Chemistry, which focused on the synthesis-structure-property-function relations of selected classes of inorganic and polymer materials. In this course we will be primarily concerned with newer methods of synthesizing inorganic solids with properties and functions specifically tailored for a particular use. The subject matter will cover aspects of modern materials chemistry. Topics are selected to introduce the student to current highlights of materials chemistry, an emerging sub-discipline of chemistry. The interrelationship of synthesis to property and function will be critically examined and how these create opportunities for new materials applications and technologies. 

 

Background 

 

Pre-requisites: CHM325H1/CHM355H1, CHM338H1

Exclusion: CHM434H1 

 

Textbook

  • TBA

 

Lecturer 

 

  • TBA

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline

Title 

CHM456H1(formerly CHM446H1) Organic Materials Chemistry (Graduate Course CHM1304H1)

Schedule 

 

2 lectures 

 

Topics 

 

This course covers design, synthesis, characterization, and application of organic materials. Emphasis is placed on classic examples of organic materials including semiconducting polymers, molecular devices, self-assembled systems, and bioconjugates, as well as recent advances from the literature. 

 

Background 

 

Prerequisite: CHM247H1/CHM249H1, CHM220H1/CHM222H1/CHM225Y1

Exclusion: CHM446H1

Recommended Preparation: CHM355H1, CHM342H1/CHM343H1

 

Textbook

 

  • Reading with be assigned from the literature, and that reading will be posted.

 

Lecturer 

 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM457H1 (formerly CHM426H1) Polymer Chemistry (Graduate Course: CHM1300H1)

Schedule 

2 lectures 
1 tutorials 

Topics 

Scope of polymer chemistry. Organic and inorganic polymers. Synthesis and characterization of polymers. Polymers as advanced materials. Polymers in solution: Flory-Huggins theory. Polymers in the solid state: crystalline and amorphous polymers, the effects of the glass transition on polymer properties, mechanical properties of polymer. 

Background 

 

Prerequisite: CHM220H1/CHM222H1/CHM225Y1, CHM247H1/CHM249H1

Exclusion: CHM426H1

Recommended Preparation: CHM355H1

 

Textbook

Required 

 

  • P.C. Painter and M.M. Coleman, ESSENTIALS OF POLYMER SCIENCE AND ENGINEERING, May 2008, ISBN 978-1-932078-75-6 

 

Course Spokesperson 

Lecturer 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline
2020-2021: Course Outline

Title 

CHM458H1 - Soft Materials for Life, Energy, and the Environment (Graduate Course: CHM1307HS) (NEW)

Schedule

2 lectures
 

Topics

Polymer characterization, polymer devices, start-ups, science communication

 

Background

 

Prerequisite: CHM247H1/CHM249H1/MSE245H1; CHM220H1/CHM222H1/CHM223H1/APS110H1
Recommended Preparation: CHM355H1; CHM342H1/CHM343H1; CHM457H1

 

Textbook

 

There is no dedicated text for this course.

Articles will be made available to complement lecture notes.

Important course materials will be regularly delivered on Quercus.

 

Lecturer

 

  • TBA
     

Course Outline

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

PHC470H1 Global Pharmaceutical Policy (Cross Listed Course: PHM320H1)

Schedule 

2 lectures 

Topics 

Access to essential medicines remains a key global public health priority and is included in the globally endorsed Sustainable Development Goals. Despite decades of global efforts, evidence indicates that there is an inconsistent pattern in the availability of essential medicines globally. High prices, poor purchasing and distribution programmes, uncertain product quality and the falsification of medicines, and inappropriate prescribing practices, are but some of the potential factors that undermine availability and equity of the global population to essential medicines.

This course is designed for students who are curious about global health issues and global pharmaceutical policy issues in particular and can engage in critical analysis. There are no prerequisites required but it does require consistent and meaningful student commitment. This includes but is not limited to the following: keeping up with assigned class readings, participation in class discussions, the preparation of a research paper, and a class presentation that is based on the research paper.

In terms of content, we start the class with an introduction to the concept of global health and the stakeholders within the global health community. We then examine specific pharmaceutical policy issues, such as equity issues related to access to medicines, the research and development of new drug therapies, with a particular focus on research & development during the COVID-19 pandemic, the risk of corruption within the health and pharmaceutical sectors, and the role of global organizations in the health system.

Background 

 

Prerequisite: Enrolled as a Year 4 student in the Pharmaceutical Chemistry Specialist program.
Exclusions: PHM320H1, PHM1124H

Textbook

  • TBA

Lecturer 

  • TBA

Course Outline 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM479H1 - Biological Chemistry (Graduate Course: CHM1008H1) 

Topics 

An in-depth examination of biological systems at the molecular level. Several complex, multi-component molecular machines with a significant role in life will be examined. For each system studied, the focus will be on understanding the chemical mechanisms that underlie the biological activities, and how these processes fit into a cellular context. 

Background 

 

Prerequisite: BCH210H1/BCH242Y1, CHM347H1

 

Textbook

 

  • No textbook required.

 

Lecturer 

 

 

Course Outline 

 

2022-2023: Course Outline - TBA
2021-2022: Course Outline

Title 

CHM499Y1 - Introduction to Chemistry Research 

Schedule 

240 labs 
Notes: Enrolment in this course is limited and application for admission should be made to the Department in the preceding Winter Session, i.e., not later than the Friday before Reading Week. The application form may be filled out electronically and a hard copy submitted to the undergraduate office. 

Topics 

An experimental or theoretical research problem under the supervision of a faculty member. Students are expected to spend approximately 240 hours during the academic year on their research problem. All students following the Chemistry Specialist program, or one of the joint specialist programs involving Chemistry (Biological Chemistry, Chemical Physics, Materials Science, Environmental Chemistry) are strongly encouraged to consider taking this course. The opportunity for doing original work in one of the branches of chemistry in the atmosphere of a research laboratory is a very valuable one, not only for prospective graduate work, but also for many other endeavours. 

Projects in the areas of environmental, analytical, physical, inorganic, materials, organic and biological chemistry are offered. Students are encouraged to visit the faculty’s website prior to submission of their applications to get some ideas of the group research and indicate their choice of areas of interest on the application. However, it is not required that a student has signed up with a research faculty when submitting an application. Only students who are offered admission will be required to interview and find a research supervisor 

Background 

Pre-requisites: Permission of the department. Minimum CGPA of 3.0. Research positions are limited. Students with strong background in courses in the sub-discipline of research interest will be given preference. 

Course Spokesperson 

Fall 2021 

Winter 2022